|
AST
|
ALP
|
Creatinine
|
GSH
|
MDA
|
PCC
|
---|
Normal control
|
68.27 ± 0.91
|
82.74 ± 1.52
|
0.81 ± 0.07
|
711.07 ± 2.20
|
37.80 ± 0.40
|
2.26 ± 0.43
|
EAC control
|
123.82 ± 1.10
|
165.30 ± 1.14
|
1.58 ± 0.11
|
668.94 ± 1.51
|
45.47 ± 1.28
|
5.16 ± 0.74
|
EAC + 1/5 LD50
A. amoreuxi venom
|
85.08 ± 0.79
|
90.02 ± 1.30
|
1.54 ± 0.05
|
729.90 ± 1.10
|
32.48 ± 0.41
|
4.23 ± 0.61
|
EAC + cisplatin (0.25 mg/kg)
|
69.34 ± 0.86
|
99.20 ± 1.73
|
1.47 ± 0.03
|
750.98 ± 0.94
|
35.24 ± 1.01
|
4.90 ± 0.66
|
1/5 LD50
A. amoreuxi venom
|
77.13 ± 1.58#
|
135.71 ± 1.02#
|
1.51 ± 0.02#
|
702.00 ± 7.89#
|
35.08 ± 4.06#
|
3.99 ± 0.24#
|
- Data are presented as mean ± SEM (six animals/group)
-
#Significant difference between animal groups (normal control EAC control, EAC + 1/5 LD50
A. amoreuxi venom, EAC + cisplatin and 1/5 LD50
A. amoreuxi venom) using one-way ANOVA (P ≤ 0.05) followed by a Tukey post hoc test for multiple comparisons