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Table 3 Effect of A. amoreuxi venom on biochemical parameters in serum and liver of EAC-bearing mice

From: In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

  AST ALP Creatinine GSH MDA PCC
Normal control 68.27 ± 0.91 82.74 ± 1.52 0.81 ± 0.07 711.07 ± 2.20 37.80 ± 0.40 2.26 ± 0.43
EAC control 123.82 ± 1.10 165.30 ± 1.14 1.58 ± 0.11 668.94 ± 1.51 45.47 ± 1.28 5.16 ± 0.74
EAC + 1/5 LD50 A. amoreuxi venom 85.08 ± 0.79 90.02 ± 1.30 1.54 ± 0.05 729.90 ± 1.10 32.48 ± 0.41 4.23 ± 0.61
EAC + cisplatin (0.25 mg/kg) 69.34 ± 0.86 99.20 ± 1.73 1.47 ± 0.03 750.98 ± 0.94 35.24 ± 1.01 4.90 ± 0.66
1/5 LD50 A. amoreuxi venom 77.13 ± 1.58# 135.71 ± 1.02# 1.51 ± 0.02# 702.00 ± 7.89# 35.08 ± 4.06# 3.99 ± 0.24#
  1. Data are presented as mean ± SEM (six animals/group)
  2. #Significant difference between animal groups (normal control EAC control, EAC + 1/5 LD50 A. amoreuxi venom, EAC + cisplatin and 1/5 LD50 A. amoreuxi venom) using one-way ANOVA (P ≤ 0.05) followed by a Tukey post hoc test for multiple comparisons