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Table 2 Effect of A. amoreuxi venom on hematological parameters of EAC-bearing mice

From: In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

  RBCs count (×106/µl) Haemoglobin (%) (g/dl) WBCs count (×103/µl) Neutrophil (%) Lymphocyte (%) Monocyte (%)
Normal control 4.06 ± 0.18 6.08 ± 0.15 2.31 ± 0.29 45.06 ± 0.39 50.48 ± 0.57 3.58 ± 0.29
EAC control 2.44 ± 0.18 3.83 ± 0.16 3.23 ± 0.37 57.43 ± 0.42 38.53 ± 0.43 3.31 ± 0.15
EAC + 1/5 LD50 A. amoreuxi venom 3.96 ± 0.0.8 6.03 ± 0.12 1.86 ± 0.23 45.41 ± 74 50.66 ± 0.84 3.21 ± 0.16
EAC + cisplatin (0.25 mg/kg) 3.23 ± 0.42 5.60 ± 0.62 3.11 ± 0.10 60.73 ± 3.14 38.75 ± 2.65 3.50 ± 0.18
1/5 LD50 A. amoreuxi venom 4.59 ± 0.08# 6.38 ± 0.32# 2.71 ± 0.26# 44.23 ± 1.73# 51.55 ± 1.76# 3.36 ± 0.20
  1. Data are presented as mean ± SEM (six animals/group)
  2. #Significant difference between animal groups (normal control EAC control, EAC + 1/5 LD50 A. amoreuxi venom, EAC + cisplatin and 1/5 LD50 A. amoreuxi venom) using one-way ANOVA (P ≤ 0.05) followed by a Tukey post hoc test for multiple comparisons