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Table 2 Effect of A. amoreuxi venom on hematological parameters of EAC-bearing mice

From: In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

 

RBCs count (×106/µl)

Haemoglobin (%) (g/dl)

WBCs count (×103/µl)

Neutrophil (%)

Lymphocyte (%)

Monocyte (%)

Normal control

4.06 ± 0.18

6.08 ± 0.15

2.31 ± 0.29

45.06 ± 0.39

50.48 ± 0.57

3.58 ± 0.29

EAC control

2.44 ± 0.18

3.83 ± 0.16

3.23 ± 0.37

57.43 ± 0.42

38.53 ± 0.43

3.31 ± 0.15

EAC + 1/5 LD50 A. amoreuxi venom

3.96 ± 0.0.8

6.03 ± 0.12

1.86 ± 0.23

45.41 ± 74

50.66 ± 0.84

3.21 ± 0.16

EAC + cisplatin (0.25 mg/kg)

3.23 ± 0.42

5.60 ± 0.62

3.11 ± 0.10

60.73 ± 3.14

38.75 ± 2.65

3.50 ± 0.18

1/5 LD50 A. amoreuxi venom

4.59 ± 0.08#

6.38 ± 0.32#

2.71 ± 0.26#

44.23 ± 1.73#

51.55 ± 1.76#

3.36 ± 0.20

  1. Data are presented as mean ± SEM (six animals/group)
  2. #Significant difference between animal groups (normal control EAC control, EAC + 1/5 LD50 A. amoreuxi venom, EAC + cisplatin and 1/5 LD50 A. amoreuxi venom) using one-way ANOVA (P ≤ 0.05) followed by a Tukey post hoc test for multiple comparisons
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