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Table 1 Effect of A. amoreuxi venom on body weight and survival time of EAC-bearing mice

From: In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

  Body weight (g) Survival time range (days) MST (days) ILS (%) T/C (%) TIR (%)
1st day 12th day
EAC control 21.20 ± 2.41 31.62 ± 3.21 12–19 15.5
EAC + 1/5 LD50 A. amoreuxi venom 20.21 ± 1.84 28.77 ± 2.33 16–23 19.5 25.80* 125.81* 25.41
EAC + cisplatin (0.25 mg/kg) 21.48 ± 2.19 28.48 ± 3.76 16–25 20.5 32.25* 132.26* 23.88
  1. Data are presented as mean ± SEM (six animals/group)
  2. * Significant difference between EAC control and treated groups using student unpaired t test (P < 0.05)