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Table 1 Effect of A. amoreuxi venom on body weight and survival time of EAC-bearing mice

From: In vitro and in vivo antitumor effects of the Egyptian scorpion Androctonus amoreuxi venom in an Ehrlich ascites tumor model

 

Body weight (g)

Survival time range (days)

MST (days)

ILS (%)

T/C (%)

TIR (%)

1st day

12th day

EAC control

21.20 ± 2.41

31.62 ± 3.21

12–19

15.5

–

–

–

EAC + 1/5 LD50 A. amoreuxi venom

20.21 ± 1.84

28.77 ± 2.33

16–23

19.5

25.80*

125.81*

25.41

EAC + cisplatin (0.25 mg/kg)

21.48 ± 2.19

28.48 ± 3.76

16–25

20.5

32.25*

132.26*

23.88

  1. Data are presented as mean ± SEM (six animals/group)
  2. * Significant difference between EAC control and treated groups using student unpaired t test (P < 0.05)
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