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Table 3 Sensitivity and specificity—HoloTC versus B12—original research conclusions

From: Holotranscobalamin (HoloTC, Active-B12) and Herbert’s model for the development of vitamin B12 deficiency: a review and alternative hypothesis

Positive conclusions

Negative or neutral conclusions

Augoustides-Savvopoulou et al. (2007)

Al Aisari et al. (2010)

Bhat et al. (2009)

Chen et al. (2005)

Black et al. (2006)

Clarke et al. (2007)

Bor et al. (2004)

Goringe et al. (2006)

Čabarkapa et al. (2007)

Loikas et al. (2003)

Fragasso et al. (2012)

Loikas (2007)

Heil et al. (2012)

Miller et al. (2006)

Herrmann et al. (2003a)

Nilsson et al. (2004)

Herrmann et al. (2005)

Palacios et al. (2013)

Herrmann and Obeid (2013)

Remacha et al. (2014)

Hvas and Nexo (2003)

Schrempf et al. (2011)

Hvas and Nexo (2005)

Sobczyńska-Malefora et al. (2014)

Lee et al. (2009)

van Asselt et al. (2003)

Lindemans et al. (2007)

 

Lindgren et al. (1999)

 

Lloyd-Wright et al. (2003)

 

Lobreglio et al. (2008)

 

Morkbak et al. (2007)

 

Nexo et al. (2002a)

 

Obeid and Herrmann (2007a)

 

Scott et al. (2007)

 

Serefhanoglu et al. (2008)

 

Sikaris (2010)

 

Valente et al. (2011)

 

Vanpoucke et al. (2007)

 

Woo et al. (2010)

 
  1. Positive, neutral or negative conclusions are as understood by this author to be the intention of authors of cited article
  2. Quotations from original reports are available in tables in Microsoft Excel spreadsheet file, Additional file 3