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Table 6 Assay data for marketed drug using internal standard of cyanocobalamine

From: Validated RP-HPLC method for simultaneous determination and quantification of chlorpheniramine maleate, paracetamol and caffeine in tablet formulation

Active pharmaceutical ingredient

Nominal concentration (µg/mL)

Mean peak area ratio

Mean actual concentration (µg/mL)

Mean content %

Chlorpheniramine maleate

0.100

0.098

0.098

98.0 ± 1.30

Paracetamol

12.500

1.022

12.775

102.2 ± 0.80

Caffeine

0.750

1.017

0.763

101.7 ± 1.10