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Table 3 Mean recovery of chlorpheniramine maleate, paracetamol and caffeine in the presence of tablet excipients

From: Validated RP-HPLC method for simultaneous determination and quantification of chlorpheniramine maleate, paracetamol and caffeine in tablet formulation

Chlorpheniramine maleate

Paracetamol

Caffeine

Amount added (µg/mL)

Mean recovery (%) ± SD

Amount added (µg/mL)

Mean recovery (%) ± SD

Amount added (µg/mL)

Mean recovery (%) ± SD

10

98.00 ± 1.30

50

102.2 ± 0.80

10

101.7 ± 1.10

20

100.95 ± 1.25

150

99.50 ± 1.50

20

100.75 ± 0.95

40

99.65 ± 0.95

300

100.90 ± 0.88

40

99.99 ± 1.25

  1. These concentrations were injected in triplicates using 1.25 µg/mL of cyanocobalamine as internal standard