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Table 2 Effects of ornithine HCl or ornithine-asparte administration to mice on the potassium levels in brain, heart, spleen, skeletal muscle, and kidney

From: Tissue-specific regulation of potassium homeostasis by high doses of cationic amino acids

  Control Ornithine HCl Ornithine aspartate
Brain 93.14 ± 1.1 108.1 ± 1.3*** 104.0 ± 1.9***
Heart 73.25 ± 1.4 84.36 ± 3.4* 78.14 ± 2.7
Spleen 112.9 ± 2.6 112.6 ± 2.0 106.0 ± 3.0
Muscle 95.14 ± 3.3 104.3 ± 3.8 104.6 ± 5.1
Kidney 69.86 ± 2.4 58.69 ± 2.0* 53.86 ± 3.2*
  1. l-Ornithine HCl (4 g/kg) or l-ornithine aspartate (6 g/kg) were given intraperitoneally (two injections, 1 h apart) to mice and tissue potassium was determined 2 h after the last injection. Results are given as mean ± SE from six animals and are expressed as µmol/g
  2. Statistical significance: (*) P < 0.05 versus control; (**) P < 0.001 versus control