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Table 2 Effects of ornithine HCl or ornithine-asparte administration to mice on the potassium levels in brain, heart, spleen, skeletal muscle, and kidney

From: Tissue-specific regulation of potassium homeostasis by high doses of cationic amino acids

 

Control

Ornithine HCl

Ornithine aspartate

Brain

93.14 ± 1.1

108.1 ± 1.3***

104.0 ± 1.9***

Heart

73.25 ± 1.4

84.36 ± 3.4*

78.14 ± 2.7

Spleen

112.9 ± 2.6

112.6 ± 2.0

106.0 ± 3.0

Muscle

95.14 ± 3.3

104.3 ± 3.8

104.6 ± 5.1

Kidney

69.86 ± 2.4

58.69 ± 2.0*

53.86 ± 3.2*

  1. l-Ornithine HCl (4 g/kg) or l-ornithine aspartate (6 g/kg) were given intraperitoneally (two injections, 1 h apart) to mice and tissue potassium was determined 2 h after the last injection. Results are given as mean ± SE from six animals and are expressed as µmol/g
  2. Statistical significance: (*) P < 0.05 versus control; (**) P < 0.001 versus control
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