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Table 5 Association of MG53 genotypes with the risk of IFG from NGT in Yixing cohort population

From: Evaluation of common variants in MG53 and the risk of type 2 diabetes and insulin resistance in Han Chinese

SNPs

Gender

Additive model

Dominant model

HR (95 % CI)a

Pa

HR (95 % CI)a

Pa

rs7186832

Whole population

1.077 (0.899–1.291)a

0.421a

1.192 (0.967–1.47)a

0.1a

Male

0.821 (0.606–1.112)b

0.202b

0.819 (0.584–1.148)b

0.247b

Female

1.283 (1.022–1.611)b

0.032b

1.556 (1.184–2.045)b

0.002b

rs12929077

Whole population

1.035 (0.869–1.234)a

0.698a

1.116 (0.908–1.373)a

0.297a

Male

0.786 (0.588–1.049)b

0.102b

0.758 (0.545–1.053)b

0.098b

Female

1.247 (0.998–1.558)b

0.052b

1.481 (1.127–1.948)b

0.005b

  1. SNP single nuclear polymorphisms, HR hazard ratio, CI confidence interval, P probability
  2. aCox regression analysis adjusted for age, gender and BMI
  3. bCox regression analysis adjusted for age and BMI