Table 4 Associations analysis of MG53 rs7186832 and rs12929077 with T2D in Wuxi population
SNP | Gender | Group | WT/Ht/MT | Additive model (WT vs Ht vs MT) | Dominant model (WT vs Ht + MT) | ||
|---|---|---|---|---|---|---|---|
OR (95 % CI) | P value | OR (95 % CI) | P value | ||||
rs7186832 | Whole population | Control | 756/392/50 | ||||
T2D | 738/391/62 | 1.03 (0.89–1.20) | 0.61 | 1.02 (0.85–1.21) | 0.81 | ||
Male | Control | 289/169/19 | |||||
T2D | 286/159/30 | 1.03 (0.82–1.30) | 0.75 | 0.97 (0.73–1.28) | 0.84 | ||
Female | Control | 467/223/31 | |||||
T2D | 452/232/32 | 1.04 (0.86–1.26) | 0.63 | 1.06 (0.84–1.33) | 0.59 | ||
rs12929077 | Whole population | Control | 726/409/56 | ||||
T2D | 716/415/69 | 1.04 (0.90–1.21) | 0.51 | 1.04 (0.87–1.24) | 0.65 | ||
Male | Control | 278/175/21 | |||||
T2D | 277/167/34 | 1.05 (0.84–1.32) | 0.64 | 0.99 (0.75–1.31) | 0.96 | ||
Female | Control | 448/234/35 | |||||
T2D | 439/248/35 | 1.05 (0.87–1.26) | 0.60 | 1.08 (0.863–1.35) | 0.49 | ||