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Table 2 Associations of MG53 rs7186832 and rs12929077 with T2D in Nantong population

From: Evaluation of common variants in MG53 and the risk of type 2 diabetes and insulin resistance in Han Chinese

SNP

Group

WT/Ht/MT

Additive model (WT vs Ht vs MT)

Dominant model (WT vs Ht + MT)

OR (95 % CI)a

OR (95 % CI)b

OR (95 % CI)c

OR (95 % CI)a

OR (95 % CI)b

OR (95 % CI)c

rs7186832

 

TT/TC/CC

      

NGT

637/282/38

1.03 (0.89–1.18)

1.03 (0.89–1.18)

1.21 (1.03–1.40)

1.06 (0.91–1.24)

1.07 (0.91–1.26)

1.31 (1.1–1.57)

IFG

360/142/20

P = 0.717

P = 0.680

P = 0.014

P = 0.489

P = 0.439

P = 0.003

T2D

502/247/26

      

rs12929077

 

AA/AG/GG

      

NGT

570/343/41

0.99 (0.86–1.13)

0.99 (0.87–1.14)

1.13 (0.98–1.32)

1.01 (0.86–1.17)

1.02 (0.87–1.19)

1.18 (1.02–1.39)

IFG

320/182/16

P = 0.850

P = 0.070

P = 0.089

P = 0.968

P = 0.825

P = 0.049

T2D

459/283/29

      
  1. SNP single nuclear polymorphisms, WT wild type, Ht heterozygote, MT mutant type, OR odds ratio, CI confidence interval, NGT normal glucose tolerance, IFG impaired fasting glucose, P probability, T2D type 2 diabetes
  2. aP value of χ2 test for comparison of genotype between case and control groups
  3. bOrdinal multinomial logistic regression analysis adjusted for age, gender and PAI
  4. cOrdinal multinomial logistic regression analysis adjusted for age, gender, BMI and PAI
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