|
Parameter
|
For all patients (n = 471)
|
For normal bilirubin patients (n = 138)
|
|---|
|
CEA
|
CA 125
|
CA 19-9
|
CEA
|
CA 125
|
CA 19-9
|
|---|
|
Cut-off value
|
4.37
|
26.84
|
200.4
|
3.36
|
25.905
|
203.96
|
|
ROC area
|
0.659
|
0.785
|
0.815
|
0.542
|
0.730
|
0.825
|
|
95 % CI
|
0.604–0.713
|
0.740–0.829
|
0.773–0.857
|
0.425–0.659
|
0.629–0.830
|
0.736–0.913
|
|
Sensitivity (%)
|
74.4
|
77
|
71.2
|
60.2
|
78.6
|
83.7
|
|
Specificity (%)
|
52.5
|
71
|
88.3
|
45
|
67.5
|
80
|
|
PPV (%)
|
74.9
|
83.2
|
92.1
|
72.8
|
85.6
|
91.1
|
|
NPV (%)
|
51.8
|
61.6
|
61.6
|
31.6
|
56.2
|
66.7
|
-
ROC receiver operating characteristic, PPV positive predictive value, NPV negative predictive value, CA 19-9 carbohydrate antigenic determinant 19-9, CA 125 carbohydrate antigen 125, CEA carcino embryonie antigen
