From: A meta-analysis of MMP-9 promoter −1562 C/T polymorphism on susceptibility of chronic periodontitis
MMP-9 (−1562 C/T) | Study majorly contributed to the heterogeneity | Heterogeneity after excluding the study | Pooled ORs of the remaining studies | |
---|---|---|---|---|
Ph | I 2, % | OR 95 % CI, P | ||
Total | ||||
T versus C | Li et al.’s study | 0.000 | 85.2 | 0.56 (0.33, 0.97), 0.040 |
CT versus CC | Li et al.’s study | 0.013 | 65.4 | 0.62 (0.39, 0.98), 0.040 |
Dominant genetic model | Li et al.’s study | 0.000 | 82.9 | 0.54 (0.29, 1.01), 0.054 |
Ethnicity | ||||
Caucasian | ||||
T versus C | Keles et al.’s study | 0.440 | 0.0 | 0.75 (0.54, 1.04), 0.080 |
Severity of chronic periodontitis | ||||
Severe | ||||
T versus C | Holla et al.’s study | 0.003 | 75.2 | 0.37 (0.25, 0.54), 0.000 |
CT versus CC | Holla et al.’s study | 0.108 | 47.3 | 0.36 (0.28, 0.47), 0.000 |
Dominant genetic mode | Holla et al.’s study | 0.003 | 75.2 | 0.32 (0.19, 0.53), 0.000 |