Table 1 Evaluation of minimum inhibitory concentration (MIC) of fluconazole (FLZ), amphotericin B (AMB) and piroctone olamine (PO) against Candida species as agents of fungemia
From: Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis
Species | Number (%) | Drugs | MIC range (μg/ml)/average |
|---|---|---|---|
Candida albicans | 10 (23.26 %) | AMB | 0.03–0.5 (0.01) |
FLZ | 0.5–16 (4.6) | ||
PO | 0.125–0.25 (0.19) | ||
C. parapsilosis | 13 (30.23 %) | AMB | 0.03–0.5 (0.10) |
FLZ | 0.5–64 (6.5) | ||
PO | 0.125–0.5 (0.24) | ||
C. tropicalis | 09 (20.93 %) | AMB | 0.03–0.06 (0.03) |
FLZ | 0.125–64 (7.77) | ||
PO | 0.125–0.5 (0.87) | ||
C. glabrata | 02 (4.65 %) | AMB | 0.03–0.03 (0.03) |
FLZ | 0.5–0.5 (0.5) | ||
PO | 0.125–0.125 (0.12) | ||
C. guilliermondii | 07 (16.28 %) | AMB | 0.03–1.0 (0.24) |
FLZ | 2.0–4.0 (2.85) | ||
PO | 0.125–0.25 (0.18) | ||
C. krusei | 02 (4.65 %) | AMB | 0.03–1.0 (0.51) |
FLZ | 16–32 (24) | ||
PO | 0.125–0.25 (0.19) |