Skip to main content

Table 1 Evaluation of minimum inhibitory concentration (MIC) of fluconazole (FLZ), amphotericin B (AMB) and piroctone olamine (PO) against Candida species as agents of fungemia

From: Antifungal activity of the piroctone olamine in experimental intra-abdominal candidiasis

Species Number (%) Drugs MIC range (μg/ml)/average
Candida albicans 10 (23.26 %) AMB 0.03–0.5 (0.01)
FLZ 0.5–16 (4.6)
PO 0.125–0.25 (0.19)
C. parapsilosis 13 (30.23 %) AMB 0.03–0.5 (0.10)
FLZ 0.5–64 (6.5)
PO 0.125–0.5 (0.24)
C. tropicalis 09 (20.93 %) AMB 0.03–0.06 (0.03)
FLZ 0.125–64 (7.77)
PO 0.125–0.5 (0.87)
C. glabrata 02 (4.65 %) AMB 0.03–0.03 (0.03)
FLZ 0.5–0.5 (0.5)
PO 0.125–0.125 (0.12)
C. guilliermondii 07 (16.28 %) AMB 0.03–1.0 (0.24)
FLZ 2.0–4.0 (2.85)
PO 0.125–0.25 (0.18)
C. krusei 02 (4.65 %) AMB 0.03–1.0 (0.51)
FLZ 16–32 (24)
PO 0.125–0.25 (0.19)