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Table 2 Participant characteristics (N = 219)

From: Polymorphisms in DNA repair and oxidative stress genes associated with pre-treatment cognitive function in breast cancer survivors: an exploratory study

Characteristic (measure)

Group A (n = 55) Mean ± SD or n (%)

Group B (n = 83) Mean ± SD or n (%)

Healthy controls (n = 81) Mean ± SD or n (%)

F or χ2 test statistic p value

Age (years)

58.76 ± 5.47

62.47 ± 5.96

60.06 ± 6.08

<.001*

Education (years)

15.67 ± 2.78

14.95 ± 3.06

14.84 ± 2.91

.232

Estimated verbal intelligence (NART-R)

108.94 ± 8.87

107.04 ± 8.84

114.72 ± 7.84

<.001*

Depression (BDI-II)

5.24 ± 6.61

4.60 ± 4.65

4.83 ± 5.52

.760

Anxiety (POMS tension-anxiety subscale)

9.61 ± 6.14

6.97 ± 4.65

6.61 ± 5.63

.004*

Fatigue (POMS fatigue-inertia subscale)

5.11 ± 5.33

5.84 ± 6.35

5.74 ± 5.99

.759

Pain (BPI)

1.47 ± 1.96

1.55 ± 2.27

0.94 ± 2.07

.144

Marital status, married

38 (69.1)

54 (65.1)

46 (56.8)

.306

Number of children

1.75 ± 1.22

2.05 ± 1.39

2.12 ± 1.53

.283

Race, Caucasian

52 (94.5)

81 (97.6)

75 (92.6)

.337

Cancer stage

 Stage 1

25 (45.5)

69 (83.1)

–

–

 Stage 2a

19 (34.5)

12 (14.5)

–

–

 Stage 2b

5 (9.1)

2 (2.4)

–

–

 Stage 3a

6 (10.9)

0 (0.0)

–

–

  1. SD, standard deviation; Group A, prescribed chemotherapy plus anastrozole; Group B, prescribed anastrozole alone; NART-R, National Adult Reading Test-Revised; BDI-II, Beck Depression Inventory-II, POMS, Profile of Mood States; BPI, Brief Pain Inventory. One-way ANOVAs utilized to compare study cohort means of continuous variables. Pearson’s Chi square tests of independence used to examine the general associations between categorical variables
  2. * p < .05