Compound | 3 h | 4 h | 5 h | 6 h | ||||
---|---|---|---|---|---|---|---|---|
Swelling | Inhibition (%) | Swelling | Inhibition (%) | Swelling | Inhibition (%) | Swelling | Inhibition (%) | |
Volume of edemac (mL) and % AId | ||||||||
Control (−) | 1.17 ± 0.032 | 1.37 ± 0.012 | 1.60 ± 0.019 | 1.89 ± 0.009 | ||||
Ibuprofen | 0.08 ± 0.021 | 93.16 | 0.06 ± 0.027 | 95.62 | 0.07 ± 0.027 | 95.62 | 0.10 ± 0.021 | 94.70 |
13a | 0.60 ± 0.015 | 48.17 | 0.60 ± 0.004 | 56.20 | 0.66 ± 0.004 | 58.75 | 0.71 ± 0.012 | 62.43 |
13b | 0.62 ± 0.024a | 47.00 | 0.61 ± 0.008a | 55.47 | 0.69 ± 0.008a | 56.87 | 0.74 ± 0.016a | 60.84 |
13c | 0.17 ± 0.020 | 85.47 | 0.17 ± 0.016 | 87.59 | 0.21 ± 0.009 | 86.87 | 0.26 ± 0.011 | 86.24 |
13d | 0.50 ± 0.007 | 57.26 | 0.49 ± 0.019 | 64.23 | 0.54 ± 0.009 | 66.25 | 0.56 ± 0.015 | 70.37 |
13e | 0.43 ± 0.011 | 63.24 | 0.42 ± 0.023 | 69.34 | 0.53 ± 0.013 | 66.87 | 0.62 ± 0.018 | 67.19 |
13f | 0.54 ± 0.015 | 53.84 | 0.54 ± 0.010 | 60.58 | 0.57 ± 0.019 | 64.37 | 0.62 ± 0.011 | 67.19 |
13g | 0.15 ± 0.017a | 87.17 | 0.12 ± 0.007a | 91.24 | 0.15 ± 0.014a | 90.62 | 0.20 ± 0.012a | 89.41 |
13h | 0.40 ± 0.022 | 65.81 | 0.49 ± 0.012 | 64.23 | 0.56 ± 0.017 | 65.00 | 0.60 ± 0.011 | 68.25 |
13i | 0.23 ± 0.009b | 80.34 | 0.20 ± 0.019b | 85.40 | 0.26 ± 0.010b | 83.75 | 0.31 ± 0.016b | 83.59 |
13j | 0.32 ± 0.012b | 72.64 | 0.34 ± 0.023b | 75.18 | 0.40 ± 0.013b | 75.00 | 0.49 ± 0.011b | 74.07 |
13k | 0.20 ± 0.010b | 82.90 | 0.19 ± 0.016b | 86.13 | 0.25 ± 0.012b | 84.37 | 0.30 ± 0.020b | 84.20 |
13l | 0.11 ± 0.019a | 90.59 | 0.09 ± 0.011a | 93.43 | 0.11 ± 0.021a | 93.12 | 0.16 ± 0.012a | 91.53 |
13m | 0.27 ± 0.024b | 76.92 | 0.26 ± 0.020b | 81.02 | 0.32 ± 0.011b | 80.00 | 0.42 ± 0.017b | 77.77 |
13n | 0.25 ± 0.006b | 78.63 | 0.21 ± 0.012b | 84.67 | 0.27 ± 0.021b | 83.12 | 0.35 ± 0.009b | 81.48 |
13o | 0.07 ± 0.011a | 94.01 | 0.05 ± 0.021a | 96.35 | 0.07 ± 0.011a | 95.62 | 0.11 ± 0.014a | 94.17 |
13p | 0.36 ± 0.010 | 69.23 | 0.40 ± 0.015 | 70.80 | 0.47 ± 0.010 | 70.62 | 0.52 ± 0.012 | 72.48 |
13q | 0.38 ± 0.019 | 67.52 | 0.45 ± 0.019 | 67.15 | 0.26 ± 0.049b | 67.50 | 0.58 ± 0.020 | 69.31 |