Table 5 Coefficient C for VDR polymorphisms and clinical data
From: Association of vitamin D receptor variants with clinical parameters in prostate cancer
SNPs | PCa | BPH | |||||||
|---|---|---|---|---|---|---|---|---|---|
Age < 58 years old | Age ≥ 58 years old | P | PSA < 10 ng/mL | PSA ≥ 10 ng/mL | P | Age < 58 years old | Age ≥ 58 years old | P | |
TaqI | |||||||||
TT | 2 (1.82) | 6 (5.45) | <0.0001* | 29 (30.21) | 15 (15.63) | 0.09 | 0 | 4 (10.81) | 0.0004* |
TC | 38 (34.55) | 8 (7.27) | 22 (22.92) | 23 (23.96) | 15 (40.54) | 6 (16.22) | |||
CC | 12 (10.91) | 44 (40.00) | 2 (2.08) | 5 (5.21) | 1 (2.70) | 11 (29.73) | |||
BsmI | |||||||||
AA | 3 (2.50) | 10 (8.33) | 0.35 | 2 (2.08) | 9 (9.38) | 0.02* | 0 | 4 (10.81) | 0.27 |
AG | 7 (5.83) | 48 (40.00) | 23 (23.96) | 20 (20.83) | 6 (16.22) | 16 (43.24) | |||
GG | 12 (10.00) | 40 (33.33) | 28 (29.17) | 14 (14.58) | 1 (2.70) | 10 (27.03) | |||
ApaI | |||||||||
GG | 1 (0.83) | 22 (18.33) | 0.71 | 18 (18.75) | 19 (19.79) | 0.30 | 1 (2.70) | 6 (16.22) | 0.07 |
GT | 14 (11.67) | 40 (33.33) | 21 (21.88) | 18 (18.75) | 2 (5.41) | 12 (32.43) | |||
TT | 7 (5.83) | 36 (30.00) | 14 (14.58) | 6 (6.25) | 4 (10.81) | 12 (32.43) | |||