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Table 3 Comparison between Linear Headache (LH) from twenty patients and Migraine from literature in demographic and clinical features

From: Linear headache: clinical characteristics of eight new cases

  Migraine (Murtaza et al. 2009)a Linear headache
Mean age at onset (years) 22 ± 15 41.8 ± 14.12
Age range at onset (years) 6–65 20–73
Female/Male ratio 141/65 = 2.16:1 12/8 = 1.5:1
Severity of pain Moderate to severe (Kelman, 2006) Moderate to severe
Pain character
Pressure-like 23.8 % 4:20 = 20 %
Distending/stretching 9.7 % 10:20 = 50 %
Throbbing/pulsating 31.6 % 6:20 = 30 %
Accompaniments
Nausea 57.8 % 8:20 = 40 %
Vomiting 32 % 4:20 = 20 %
Diziness 17 % 4:20 = 20 %
Photophobia 51.9 % 1:20 = 5 %
Phonophobia 58.7 % 1:20 = 5 %
Average episode duration (h)
Less than 2 h 23.4 % 7:20 = 35 %
Half day (2–10 h) 41.4 % 7:20 = 35 %
1 day (10–24 h) 14.1 % 6:20 = 30 %
More than 1 day (>24 h) 21.1 % 7:20 = 35 %
Triggered by
Noise, bright night, depression, fatigue and resting after physical activity Yes Yes
Stress, staying up late Yes Yes
Menstruation Common (Miziara et al. 2003) Common
Treatment requirement Approximate half patients (MacGregor et al. 2003) Most cases
Treatment
Response to flunarizine Most patients (Luo et al. 2012) Common
Response to sodium valproate Most patients (MacGregor et al. 2003), and recommendation with level A evidence (Silberstein et al. 2012) Common
Response to carbamazepine Possibably effective in some patients with no new evidence (Silberstein et al. 2012) No response
Response to oxcarbazepine No response (Silberstein et al. 2008) No response
  1. aApart from the references indicated in migraine column, all other data in this column are from reference (Murtaza et al. 2009)