Table 4 Activity of CYP enzymes and prescribed drugs potentially influenced by CYP polymorphisms (n = 51)
CYP enzyme | Enzyme activity | Drug | Number |
|---|---|---|---|
CYP2C9 | Intermediate (n = 11) | Warfarin | 1 |
Losartan | 1 | ||
Poor (n = 3) | Warfarin | 1 | |
CYP2C19 | Intermediate (n = 10) | Proton-pump inhibitor | 4 |
Diazepam | 1 | ||
Poor (n = 2) | Proton-pump inhibitor | 1 | |
Diazepam | 1 | ||
Increased (n = 1) | Escitalopram | 1 | |
CYP2D6 | Intermediate (n = 24) | Metoprolol | 14 |
Codeine | 3 | ||
Tricyclic antidepressants | 2 | ||
Tolterodine | 1 | ||
Tramadol | 1 | ||
Poor (n = 4) | Metoprolol | 2 | |
Bisoprolol | 1 | ||
Tricyclic antidepressants | 1 |