Fig. 4

Effects of active components of Radix Scrophulariae (ACRS) on phospho-specific extracellular signa lregulated kinase (ERK 1/2), phospho-specific c-Jun N-terminal kinase (JNK) and phospho-p38 mitogen-activated protein kinases (p38 MAPK) in spontaneously hypertensive rats (SHR) and Wistar–Kyoto rats (WKY). a Representative western blot analysis is shown. b Densitometric evaluation of ERK 1/2 is shown. c Densitometric evaluation of JNK is shown. d Densitometric evaluation of p38 MAPK is shown. A WKY control; B WKY+ 140 mg/kg ACRS; C SHR control; D SHR+ 40 mg/kg captopril; E SHR+ 70 mg/kg ACRS; F SHR+ 140 mg/kg ACRS; G SHR +280 mg/kg ACRS. \(\bar{x}\) ± SE, n = 6. Compared with WKY control group, ^†† P < 0.01. Compared with SHR control group, *P < 0.05; **P < 0.01