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Table 1 Descriptive data from pregnancy and follow-up in relation to glucose category 5 years after GDM

From: Model for individual prediction of diabetes up to 5 years after gestational diabetes mellitus

 

NGT (n = 187)

IFG (n = 75)

P*

IGT (n = 72)

P*

Diabetes (n = 28)

P*

Non-European origin

23 (13)

10 (15)

0.84

12 (18)

0.42

13 (48)

<0.001

First-grade diabetes heredity

47 (28)

24 (36)

0.27

28 (44)

0.027

16 (62)

0.001

Age at delivery (years)

32.1 (29.1–36.0)

32.3 (28.8–35.9)

0.99

34.6 (32.2–36.8)

0.002

35.4 (28.8–38.2)

0.060

Pregnancy

2-h PG (mmol/L)

9.3 (8.9–9.9)

9.3 (8.9–10.3)

0.43

9.5 (9.1–10.3)

0.083

10.1 (9.6–10.8)

<0.001

Diagnosis in early gestation

8 (5.0)

5 (7.9)

0.53

7 (12)

0.13

6 (23)

0.006

Insulin treatment

12 (6.5)

7 (9.3)

0.44

8 (11)

0.20

6 (21)

0.018

12 years after pregnancy

Interval to follow-up (years)

1.3 (1.0–1.7)

1.2 (1.0–1.5)

0.15

1.4 (1.2–1.6)

0.12

1.4 (1.1–1.7)

0.68

Deliveries >3

7 (4.0)

6 (8.5)

0.20

5 (7.2)

0.33

3 (10.7)

0.14

BMI (kg/m2)

23.0 (21.2–26.0)

24.1 (21.6–27.5)

0.010

24.4 (22.2–27.1)

0.011

27.0 (25.1–31)

<10−6

FPG (mmol/L)

5.2 (4.9–5.6)

5.6 (5.2–6.0)

<10−4

5.3 (5.0–5.8)

0.12

5.7 (5.2–6.3)

<0.001

2-h PG (mmol/L)

5.8 (5.0–6.9)

6.4 (5.5–7.0)

0.043

7.4 (6.1–8.3)

<10−8

7.2 (6.9–8.5)

<10−6

5 years after pregnancy

Interval to follow-up (years)

5.1 (5.0–5.2)

5.1 (5.0–5.3)

0.95

5.1 (5.0–5.3)

0.39

5.2 (5.0–5.5)

0.28

Deliveries >3

13 (7.0)

9 (12.0)

0.22

10 (13.9)

0.09

5 (18)

0.066

BMI (kg/m2)

23.4 (21.3–26.8)

25.0 (22.7–27.9)

0.005

25.8 (23.1–27.9)

0.001

28.0 (26.8–34.6)

<10−7

FPG (mmol/L)

5.5 (5.3–5.8)

6.3 (6.2–6.5)

<10−35

6.0 (5.6–6.4)

<10−10

7.1 (6.8–7.2)

<10−15

2-h PG (mmol/L)

7.4 (6.6–8.0)

7.7 (7.3–8.2)

0.003

9.7 (9.2–10.3)

<10−34

12.2 (9.5–12.7)

<10−13

  1. Data given are n (%) or median (interquartile range)
  2. Differences were tested with Fisher’s exact test (categorical variables) or the Mann–Whitney U test (continuous variables)
  3. GDM gestational diabetes mellitus, NGT normal glucose tolerance, IFG impaired fasting glucose, IGT impaired glucose tolerance, PG plasma glucose, FPG fasting plasma glucose
  4. * All comparisons were performed against NGT