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Table 2 Comparison of ROC and MPM thresholds using logistic regression analysis

From: Predicting the occurrence of major adverse cardiac events within 30 days of a vascular surgery: an empirical comparison of the minimum p value method and ROC curve approach using individual patient data meta-analysis

Models and predictors

OR (95 % CI)

p

AUC

AIC

ROC threshold

 BNP ≥ 116 pg/ml or NTproBNP ≥ 277.5 pg/ml;

8.4 (4.98,14.11)

<0.001

0.768

431.63

 Ref = BNP < 116 or NTproBNP < 277.5 pg/ml

Surgery type

 Aortoiliac; Ref = Infrainguinal surgery

2.4 (1.33, 4.37)

0.004

  

Diabetes

 Yes; Ref = No

2.0 (1.10, 3.54)

0.023

  

MPM threshold

 BNP ≥ 115.57 pg/ml or NTproBNP ≥ 246.7 pg/ml;

8.5 (5.03, 14.41)

<0.001

0.777

430.16

 Ref = BNP < 115.57 pg/ml or NTproBNP < 246.7 pg/ml

Surgery type

 Aortoiliac; Ref = Infrainguinal surgery

2.5 (1.40, 4.60)

0.002

  

Diabetes

 Yes; Ref = No

2.1 (1.15, 3.71)

0.015

  
  1. ROC threshold is an indicator variable of BNP and NTproBNP thresholds determined by the ROC curve method (Allison 2012); MPM threshold is an indicator variable of BNP and NTproBNP thresholds determined by the minimum p value method
  2. Ref reference level, OR odds ratio, CI confidence interval, AUC area under the ROC curve