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Table 3 Analysis of glucocorticoids efficacy and single nucleotide polymorphisms of HSP90AA1 gene

From: Single nucleotide polymorphisms of HSP90AA1 gene influence response of SLE patients to glucocorticoids treatment

Polymorphisms Dominant model Recessive model
Crude OR (95 % CI) Crude P value Adjusted OR (95 % CI) Adjusted P value Crude OR (95 % CI) Crude P value Adjusted OR (95 % CI) Adjusted P value
rs2298878 1.426 (0.499–4.070) 0.508 1.508 (0.516–4.405) 0.453
rs7157967 0.478 (0.091–2.515) 0.384 0.380 (0.065–2.212) 0.282
rs7160651 0.514 (0.297–0.890) 0.018 0.518 (0.293–0.916) 0.024 0.805 (0.221–2.932) 0.743 0.946 (0.251–3.564) 0.935
rs10873531 0.516 (0.305–0.876) 0.014 0.522 (0.304–0.898) 0.019 1.072 (0.375–3.059) 0.897 1.259 (0.425–3.729) 0.678
rs1190597 0.596 (0.273–1.301) 0.194 0.562 (0.251–1.259) 0.162 0.606 (0.054–6.775) 0.684 0.473 (0.040–5.611) 0.553
rs11547523 0.764 (0.341–1.712) 0.513 0.795 (0.349–1.813) 0.586
rs2298877 0.543 (0.317–0.928) 0.026 0.558 (0.323–0.967) 0.037 1.235 (0.419–3.639) 0.702 1.429 (0.466–4.380) 0.532