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Table 2 Genotype frequencies of single nucleotide polymorphisms in HSP90AA1 gene

From: Single nucleotide polymorphisms of HSP90AA1 gene influence response of SLE patients to glucocorticoids treatment

Polymorphisms (Minor allele) Sensitive (n = 128) Insensitive (n = 105) Overall (n = 233) HWE P value
Wild type Heterozygous Homozygous mutants Wild type Heterozygous Homozygous mutants Wild type Heterozygous Homozygous mutants
rs2298878 (A) 121 (94.53) 7 (5.47) 0 (0) 97 (92.38) 8 (7.62) 0 (0) 218 (93.56) 15 (6.44) 0 (0) 0.612
rs7157967 (C) 123 (96.09) 5 (3.91) 0 (0) 103 (98.10) 2 (1.90) 0 (0) 226 (97.00) 7 (3.00) 0 (0) 0.816
rs7160651 (A) 72 (56.25) 50 (39.06) 6 (4.69) 75 (71.43) 26 (24.76) 4 (3.81) 147 (63.09) 76 (32.62) 10 (4.29) 0.964
rs10873531 (G) 61 (47.66) 59 (46.09) 8 (6.25) 67 (63.81) 31 (29.52) 7 (6.67) 128 (54.94) 90 (38.63) 15 (6.43) 0.877
rs1190597 (G) 107 (83.59) 19 (14.85) 2 (1.56) 94 (89.53) 10 (9.52) 1 (0.95) 201 (86.26) 29 (12.45) 3 (1.29) 0.112
rs11547523 (G) 111 (86.72) 16 (12.50) 1 (0.78) 94 (89.52) 11 (10.48) 0 (0) 205 (87.98) 27 (11.59) 1 (0.43) 0.913
rs2298877 (T) 68 (53.13) 53 (41.41) 7 (5.46) 71 (67.62) 27 (25.71) 7 (6.67) 139 (59.66) 80 (34.33) 14 (6.01) 0.585