Skip to main content

Table 3 DNA fragmentation, p53 and caspase 3 levels of liver tissues

From: The hepatocurative effects of Cynara scolymus L. leaf extract on carbon tetrachloride-induced oxidative stress and hepatic injury in rats

Groups (n = 7)

DNA fragmentation (%)

p53 (pg/ml)

Caspase 3 (ng/ml)

Control

20.11 ± 2.69+++

55.53 ± 0.93+++

5.03 ± 0.73+++

Olive oil

20.21 ± 0.82+++

53.34 ± 0.84+++

5.11 ± 0.85+++

Cynara extract

20.07 ± 1.83+++

55.90 ± 7.94+++

4.67 ± 0.29+++

0.2 ml/kg CCl4

33.96 ± 0.35***

112.39 ± 0.20***

7.42 ± 0.12***

Recovery

29.18 ± 2.61***, +++

71.74 ± 10.39***, +++

6.75 ± 0.29***

Curative

25.66 ± 2.15***, +++, b

61.96 ± 5.96+++, a

5.04 ± 0.13+++, c

  1. * P < 0.05, ** P < 0.01, *** P < 0.001 values are compared with the control group
  2. + P < 0.05, ++ P < 0.01, +++ P < 0.001 values are compared with the CCl4 group
  3. a P < 0.05, b P < 0.01, c P < 0.001 values compared between recovery and curative group