|
Groups (n = 7)
|
DNA fragmentation (%)
|
p53 (pg/ml)
|
Caspase 3 (ng/ml)
|
|---|
|
Control
|
20.11 ± 2.69+++
|
55.53 ± 0.93+++
|
5.03 ± 0.73+++
|
|
Olive oil
|
20.21 ± 0.82+++
|
53.34 ± 0.84+++
|
5.11 ± 0.85+++
|
|
Cynara extract
|
20.07 ± 1.83+++
|
55.90 ± 7.94+++
|
4.67 ± 0.29+++
|
|
0.2 ml/kg CCl4
|
33.96 ± 0.35***
|
112.39 ± 0.20***
|
7.42 ± 0.12***
|
|
Recovery
|
29.18 ± 2.61***, +++
|
71.74 ± 10.39***, +++
|
6.75 ± 0.29***
|
|
Curative
|
25.66 ± 2.15***, +++, b
|
61.96 ± 5.96+++, a
|
5.04 ± 0.13+++, c
|
- * P < 0.05, ** P < 0.01, *** P < 0.001 values are compared with the control group
-
+ P < 0.05, ++ P < 0.01, +++ P < 0.001 values are compared with the CCl4 group
-
a P < 0.05, b P < 0.01, c P < 0.001 values compared between recovery and curative group
