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Table 3 DNA fragmentation, p53 and caspase 3 levels of liver tissues

From: The hepatocurative effects of Cynara scolymus L. leaf extract on carbon tetrachloride-induced oxidative stress and hepatic injury in rats

Groups (n = 7) DNA fragmentation (%) p53 (pg/ml) Caspase 3 (ng/ml)
Control 20.11 ± 2.69+++ 55.53 ± 0.93+++ 5.03 ± 0.73+++
Olive oil 20.21 ± 0.82+++ 53.34 ± 0.84+++ 5.11 ± 0.85+++
Cynara extract 20.07 ± 1.83+++ 55.90 ± 7.94+++ 4.67 ± 0.29+++
0.2 ml/kg CCl4 33.96 ± 0.35*** 112.39 ± 0.20*** 7.42 ± 0.12***
Recovery 29.18 ± 2.61***, +++ 71.74 ± 10.39***, +++ 6.75 ± 0.29***
Curative 25.66 ± 2.15***, +++, b 61.96 ± 5.96+++, a 5.04 ± 0.13+++, c
  1. * P < 0.05, ** P < 0.01, *** P < 0.001 values are compared with the control group
  2. + P < 0.05, ++ P < 0.01, +++ P < 0.001 values are compared with the CCl4 group
  3. a P < 0.05, b P < 0.01, c P < 0.001 values compared between recovery and curative group