Fig. 1From: An intrapleural administration of zoledronic acid for inoperable malignant mesothelioma patients: a phase I clinical study protocolGrowth of subcutaneous tumors developed in BALB/c mice. MSTO-211H cells (3 × 106) were subcutaneously inoculated and the mice were injected with PBS or ZOL (15 or 50 μg) in the intraperitoneal cavity twice a week after day 11. Tumor volume was calculated according to the formula (1/2 × length × width2). The tumor volumes were not statistically different at any time in any groups. The average and SE bars are shown (n = 6)Back to article page