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Table 2 Successful home administration of evolocumab in THOMAS-1 and THOMAS-2

From: Evolocumab lowers LDL-C safely and effectively when self-administered in the at-home setting

 

THOMAS-1

THOMAS-2

Autoinjector (n = 74)

PFS (n = 75)

Autoinjector (n = 82)

AMD (n = 82)

First administrationa

 No. successful administrations

71

73

77

78

 % (95 % CI)

95.9 (88.7, 98.6)

97.3 (90.8, 99.3)

93.9 (86.5, 97.4)

95.1 (88.1, 98.1)

Second administrationb

 No. successful administrations

68

72

76

79

 % (95 % CI)

91.9 (83.4, 96.2)

96.0 (88.9, 98.6)

92.7 (84.9, 96.6)

96.3 (89.8, 98.7)

  1. AMD automated minidoser, CI confidence interval, PFS prefilled syringe
  2. aWeek 2 in THOMAS-1, week 4 in THOMAS-2
  3. bWeek 4 in THOMAS-1, week 8 in THOMAS-2