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Table 2 Optimization on the product yield using Bi(NO₃)₃·5H₂O

From: Synthesis of hexahydrofuro[3,2-c]quinoline, a martinelline type analogue and investigation of its biological activity

Entry	Solvent	Reaction time (h)	Yield (%)
1^a	ACN	1.5	6.8
2^b	ACN	1.5	10.2
3	ACN	1.5	19.6
4	CH₂Cl₂	1.5	17.1
5	Water	1.5	9.1
6^c	Water	1.5	12.0
7	Ethanol	1.5	22.2
8^d	ACN	1.5	21.8
9	Ethanol	0.5	26.8
10	Ethanol	3	25.3
11	Ethanol	7	18.6

All the reactions were carried out at room temperature and catalyst (0.2 mol equiv) was added
^aCatalyst (0.05 mol equiv) was added
^bCatalyst (0.1 mol equiv) was added
^c0.1 M nitric acid was used and no metal catalyst was added
^dThe reaction was carried out under reflux

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