Fig. 4From: Multicentric reticulohistiocytosis (MRH): case report with review of literature between 1991 and 2014 with in depth analysis of various treatment regimens and outcomesThe multinucleated histiocytes (arrows) are large with an eosinophilic and finely granular “ground-glass” cytoplasm. The nuclei are haphazardly arranged, but tend to favor the center of the cells. A CD163 stain was diffusely positive and the cells were focally PAS-positive diastase-resistantBack to article page