Table 1 Clinical and laboratory characteristics of ADPKD patients and control subjects
ADPKD patients (n = 55) | Controls (n = 50) | p value | |
|---|---|---|---|
Age (years) | 38 ± 11.4 | 38.6 ± 10.1 | 0.674 |
Gender (males/females) | 26/29 | 24/26 | 0.548 |
Body mass index (kg/m2) | 24.1 ± 3.4 | 23.1 ± 2.9 | 0.327 |
Smoking (%) | 34 | 34.5 | 0.559 |
Systolic blood pressure (mmHg)a | 123.2 ± 10.1 | 122.9 ± 7.4 | 0.873 |
Diastolic blood pressure (mmHg)a | 75.7 ± 9.1 | 76.8 ± 6.8 | 0.499 |
BUN (mg/dL) | 12 (8–28) | 11 (7–24) | 0.176 |
Creatinine (mg/dL) | 0.76 ± 0.16 | 0.75 ± 0.11 | 0.881 |
Estimated GFR (mL/min) | 107 ± 17 | 111 ± 17 | 0.270 |
Total cholesterol (mg/dL) | 180 ± 28 | 179 ± 24 | 0.352 |
HDL cholesterol (mg/dL) | 43.8 ± 8.4 | 45 ± 9.3 | 0.569 |
LDL cholesterol (mg/dL) | 106 ± 28 | 104 ± 30 | 0.404 |
Triglycerides (mg/dL) | 114 (44–700) | 115 (43–333) | 0.985 |
Uric acid (mg/dL) | 4.8 ± 1.5 | 3.2 ± 0.9 | <0.001 |
hs-CRP (mg/dL) | 0.42 (0.22–1.19) | 0.31 (0.13–0.9) | <0.001 |
Left ventricul ejection fraction (%) | 72 (60–82) | 70 (65–82) | 0.009 |
Left ventricular mass (g) | 188 ± 55 | 154 ± 36 | <0.001 |
CIMT (mm) | 0.7 (0.4–1.2) | 0.5 (0.4–0.8) | <0.001 |
EAT thickness (mm) | 6.8 ± 2.7 | 4.8 ± 1.2 | <0.001 |