Skip to main content

Table 1 Clinical and laboratory characteristics of ADPKD patients and control subjects

From: Early atherosclerosis in normotensive patients with autosomal dominant polycystic kidney disease: the relation between epicardial adipose tissue thickness and carotid intima-media thickness

  ADPKD patients (n = 55) Controls (n = 50) p value
Age (years) 38 ± 11.4 38.6 ± 10.1 0.674
Gender (males/females) 26/29 24/26 0.548
Body mass index (kg/m2) 24.1 ± 3.4 23.1 ± 2.9 0.327
Smoking (%) 34 34.5 0.559
Systolic blood pressure (mmHg)a 123.2 ± 10.1 122.9 ± 7.4 0.873
Diastolic blood pressure (mmHg)a 75.7 ± 9.1 76.8 ± 6.8 0.499
BUN (mg/dL) 12 (8–28) 11 (7–24) 0.176
Creatinine (mg/dL) 0.76 ± 0.16 0.75 ± 0.11 0.881
Estimated GFR (mL/min) 107 ± 17 111 ± 17 0.270
Total cholesterol (mg/dL) 180 ± 28 179 ± 24 0.352
HDL cholesterol (mg/dL) 43.8 ± 8.4 45 ± 9.3 0.569
LDL cholesterol (mg/dL) 106 ± 28 104 ± 30 0.404
Triglycerides (mg/dL) 114 (44–700) 115 (43–333) 0.985
Uric acid (mg/dL) 4.8 ± 1.5 3.2 ± 0.9 <0.001
hs-CRP (mg/dL) 0.42 (0.22–1.19) 0.31 (0.13–0.9) <0.001
Left ventricul ejection fraction (%) 72 (60–82) 70 (65–82) 0.009
Left ventricular mass (g) 188 ± 55 154 ± 36 <0.001
CIMT (mm) 0.7 (0.4–1.2) 0.5 (0.4–0.8) <0.001
EAT thickness (mm) 6.8 ± 2.7 4.8 ± 1.2 <0.001
  1. ADPKD autosomal dominant polycystic kidney disease, GFR glomerular filtration rate, CIMT carotid intima-media thickness, EAT epicardial adipose tissue, hs-CRP high sensitive C-reactive protein, HDL high density lipoprotein, LDL Low density lipoprotein
  2. aBlood pressure measurements were performed at the office
  3. The results in italics identify the statistically significant values