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Table 3 Pooled OR of the OGG1 Ser326Cys polymorphism based on different types of cancer

From: Association between OGG1 Ser326Cys polymorphism and risk of upper aero-digestive tract and gastrointestinal cancers: a meta-analysis

Type of cancer

No. of studies

Case/Control

Dominant model

Recessive model

Homozygous model

OR (95 % CI)

Pa

OR (95 % CI)

Pa

OR (95 % CI)

Pa

Head and neck

6

1479/1589

1.3 (0.99–1.73)

<0.05*

1.37 (1.09–1.73)

0.007*

1.69 (1.06–2.68)

0.02*

Gastric

3

450/908

0.9 (0.71–1.14)

0.39

0.78 (0.47–1.29)

0.34

0.76 (0.45–1.27)

0.3

Colorectal

5

2479/3130

1.29 (0.9–1.84)

0.15

1.34 (1.05–1.71)

0.01*

1.38 (1.08–1.77)

0.009*

  1. aP heterogeneity
  2. * Significant at P < 0.05