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Table 2 Pooled OR of the OGG1 Ser326Cys polymorphism based on ethnicity, sample size and cancer type

From: Association between OGG1 Ser326Cys polymorphism and risk of upper aero-digestive tract and gastrointestinal cancers: a meta-analysis

Variables No. of studies Case/control Dominant model Recessive model Homozygous model
OR (95 % CI) Pa OR (95 % CI) Pa OR (95 % CI) Pa
Ethnicity
 Asian 6 1161/1407 1.21 (0.93–1.56) 0.15 1.40 (1.09–1.80) 0.009* 1.56 (1.15–2.11) 0.004*
 Caucasian 11 4372/5427 1.22 (1.01–1.48) 0.03* 1.29 (0.95–1.76) 0.104 1.40 (0.97–2.03) 0.07
Sample size
 <500 8 943/1474 1.31 (0.93–1.85) 0.122 1.64 (1.14–2.35) 0.007* 1.83 (1.01–3.29) 0.044*
 ≥500 9 4590/5360 1.16 (0.99–1.35) 0.06 1.23 (1.05–1.44) 0.012* 1.32 (0.99–1.76) 0.06
Cancer type
 GI 11 4054/5245 1.17 (0.97–1.40) 0.09 1.28 (0.95–1.74) 0.103 1.36 (0.96–1.92) 0.08
 UADT 6 1479/1589 1.32 (1–1.74) <0.05* 1.37 (1.09–1.73) <0.05* 1.74 (1.08–2.80) 0.02*
  1. aP heterogeneity
  2. * Significant at P < 0.05