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Fig. 5 | SpringerPlus

Fig. 5

From: Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway

Fig. 5

Effect of ethyl pyruvate (EP) on the expression of RAGE and NF-ΚB pathway. The sham mice and AVMC mice were intraperitoneally administrated with Ringer’s lactate solution (RLS) or 80 mg/kg/day EP from day 5 to day 7 post-infection. a Immunoblot for the expression of RAGE, phospho (p)-NF-ΚB p65, NF-ΚB p65, p-IΚBα and I-ΚBα. be Quantification of RAGE (b), p-NF-ΚB p65 (c), p-IΚBα (d) and I-ΚBα (e). Data were shown as mean ± SE from 6 to 12 individual experiments. *P < 0.01 versus Sham + RLS; # P < 0.05 versus Sham + EP; $ P < 0.05 versus AVMC + RLS

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