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Fig. 3 | SpringerPlus

Fig. 3

From: Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway

Fig. 3

Effect of ethyl pyruvate (EP) on inflammatory lesions in heart tissues of CVB3-induced AVMC. The sham mice and AVMC mice were intraperitoneally administrated with Ringer’s lactate solution (RLS) or EP (40 or 80 mg/kg/day) from the 5th day to the 7th day post-infection. a A representative HE staining for inflammatory lesions in the heart tissues (×200, arrow). b Quantification of inflammatory lesions. Data were shown as mean ± SE from 6 to 12 individual experiments. *P < 0.01 versus Sham + RLS. #P < 0.01 versus AVMC + RLS. $P < 0.01 versus AVMC + EP (40 mg/kg/day)

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