Table 3 Special categories of patients recommended for exclusion from the compulsory generic substitution (Lamy 1986; Krämer et al. 2007; Crawford et al. 2006)
Special categories | Examples |
|---|---|
High risk patients | Extreme age groups, pregnant women, patients with multiple disorders being treated with several drugs, solitary individual, etc. |
High risk diseases | Chronic diseases, diseases aggravated after the administration of drugs prescribed for co-morbid condition, etc. |
High risk drugs | Narrow therapeutic index drugs, drugs requiring individualization of dose, drugs exhibiting severe drug–drug interactions, drugs with the complex therapeutic regimen, drugs initiating the prescribing cascade, etc. |