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Table 1 The allele frequency of SNPs in PROC in patients with PE and the controls

From: Genetic association of PROC variants with pulmonary embolism in Northern Chinese Han population

SNPs Allele Hardy–Weinberg equilibrium Minor allele frequency (%) Univariate analysis Multivariate analysisa
The cases The controls Case Control OR (95% CI) P OR (95% CI) P
GENO P GENO P
rs1799809 A>G 5/25/71 0.170 9/61/198 0.140 0.173 0.147 1.212 (0.784–1.874) 0.424 1.131 (0.714–1.791) 0.599
rs199469469 AAG>del 0/9/91 1.000 0/5/263 1.000 0.045 0.009 5.004 (1.656–15.120) 0.004 5.339 (1.470–19.390) 0.011
rs2069928 G>T 11/45/45 1.000 28/117/121 1.000 0.332 0.325 1.030 (0.730–1.453) 0.861 1.102 (0.759–1.601) 0.609
rs7580688 A>G 16/54/29 0.310 38/119/94 1.000 0.434 0.388 1.209 (0.866–1.687) 0.267 1.270 (0.867–1.859) 0.219
rs2240817 A>G 4/28/69 0.510 6/83/171 0.400 0.178 0.183 0.970 (0.635–1.482) 0.915 1.187 (0.742–1.899) 0.476
rs3771293 A>G 4/37/60 0.770 10/79/171 0.840 0.223 0.190 1.219 (0.819–1.813) 0.351 1.155 (0.739–1.805) 0.528
  1. SNPs single nucleotide polymorphisms, CI confidence interval, OR odds ratio
  2. aAdjusted for sex and age