Table 1 The allele frequency of SNPs in PROC in patients with PE and the controls
From: Genetic association of PROC variants with pulmonary embolism in Northern Chinese Han population
SNPs | Allele | Hardy–Weinberg equilibrium | Minor allele frequency (%) | Univariate analysis | Multivariate analysisa | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
The cases | The controls | Case | Control | OR (95% CI) | P | OR (95% CI) | P | ||||
GENO | P | GENO | P | ||||||||
rs1799809 | A>G | 5/25/71 | 0.170 | 9/61/198 | 0.140 | 0.173 | 0.147 | 1.212 (0.784–1.874) | 0.424 | 1.131 (0.714–1.791) | 0.599 |
rs199469469 | AAG>del | 0/9/91 | 1.000 | 0/5/263 | 1.000 | 0.045 | 0.009 | 5.004 (1.656–15.120) | 0.004 | 5.339 (1.470–19.390) | 0.011 |
rs2069928 | G>T | 11/45/45 | 1.000 | 28/117/121 | 1.000 | 0.332 | 0.325 | 1.030 (0.730–1.453) | 0.861 | 1.102 (0.759–1.601) | 0.609 |
rs7580688 | A>G | 16/54/29 | 0.310 | 38/119/94 | 1.000 | 0.434 | 0.388 | 1.209 (0.866–1.687) | 0.267 | 1.270 (0.867–1.859) | 0.219 |
rs2240817 | A>G | 4/28/69 | 0.510 | 6/83/171 | 0.400 | 0.178 | 0.183 | 0.970 (0.635–1.482) | 0.915 | 1.187 (0.742–1.899) | 0.476 |
rs3771293 | A>G | 4/37/60 | 0.770 | 10/79/171 | 0.840 | 0.223 | 0.190 | 1.219 (0.819–1.813) | 0.351 | 1.155 (0.739–1.805) | 0.528 |