From: Recurrent ectopic pregnancy as a unique clinical sub group: a case control study
Recurrent ectopic | Primary ectopic | ||||
---|---|---|---|---|---|
Mean (±SD) or % (n) | Mean (±SD) or % (n) | p value | Mean difference or odds ratio | 95 % CI | |
Baseline characteristics of women with EP | |||||
Agea | 32.2 (5.08) | 30.5 (5.83) | 0.0049 | −1.65 | −2.78 to −0.51 |
Parity 1b | |||||
P0 | 37.5 (33/88) | 44.7 (327/732) | 0.2127 | 0.7431 | 0.471 to 1.172 |
P1–P3 | 54.5 (48/88) | 51.8 (379/732) | 0.6526 | 1.118 | 0.717 to 1.742 |
P4 or more | 8.0 (7/88) | 3.6 (26/732) | 0.0755 | 2.347 | 0.9872 to 5.578 |
Gestationa | 5.99 (1.08) | 6.52 (1.81) | 0.0001 | 0.5402 | 0.2728 to 0.8076 |
Risk factors for EP in women with primary and recurrent EP | |||||
Smoking | 18.7 (17/91) | 14.6 (108/741) | 0.3498 | 1.346 | 0.7650 to 2.370 |
Previous tubal surgery | 61.4 (54/88) | 3.5 (26/740) | <0.0001 | 43.62 | 24.40 to 77.97 |
Previous pelvic surgery | 53.8 (49/91) | 14.0 (104/743) | <0.0001 | 7.168 | 4.519 to 11.37 |
Previous miscarriage | 27.5 (25/91) | 24.1 (179/742) | 0.5185 | 1.191 | 0.7297 to 1.945 |
Previous TOP | 14.3 (13/91) | 18.7 (139/743) | 0.3875 | 0.7242 | 0.3913 to 1.340 |
Assisted reproduction | 3.3 (3/91) | 4.3 (32/743) | 1.0 | 0.7575 | 0.2272 to 2.526 |
Previous infertility | 12.1 (11/91) | 7.8 (58/743) | 0.1602 | 1.624 | 0.8186 to 3.222 |
Previous PID | 8.8 (8/91) | 7.7 (57/742) | 0.6794 | 1.158 | 0.5339 to 2.513 |
IUD | 0 % | 1.3 % (10/733) | 0.6121 | 2.62 | 0.1521 to 45.11 |
Mirena coil | 0 % | 0.9 % (7/743) | 1 | 1.864 | 0.1055 to 32.92 |
Clinical presentation of women with primary and recurrent EP | |||||
Painb | 93.4 (85/91) | 94.5 (705/746) | 0.63 | 0.8239 | 0.3397 to 1.998 |
Bleedingb | 80.2 (73/91) | 85.0 (634/746) | 0.2239 | 0.7164 | 0.4118 to 1.246 |
Vomitingb | 7.7 (7/91) | 9.7 (72/746) | 0.7041 | 0.7801 | 0.3475 to 1.751 |
Diarrhoeab | 0 (0/91) | 1.9 (14/746) | 0.3849 | 0.2761 | 0.01632 to 4.670 |
Shoulder tip painb | 4.4 (4/91) | 10.5 (78/745) | 0.0899 | 0.3932 | 0.1404 to 1.101 |
Syncopal attackb | 6.6 (6/91) | 11.1 (83/745) | 0.2112 | 0.563 | 0.2385 to 1.329 |
1st βHCGa | 3176 (7350) | 6243 (12,282) | 0.0099 | 3053 | 750 to 5355 |
TVSb | 95.6 (87/91) | 88.3 (651/737) | 0.0323 | 0.348 | 0.1246 to 0.9724 |
TASb | 12.1 (11/91) | 17.1 (126/738) | 0.2943 | 1.497 | 0.7747 to 2.894 |
Both TVS and TASb | 11.0 (10/91) | 12.0 (88/735) | 1 | 1.102 | 0.5505 to 2.205 |
Ultrasound scan findings | |||||
Adnexal massb | 84.6 (77/91) | 88.6 (643/726) | 0.3007 | 1.409 | 0.7624 to 2.602 |
Gest sacb | 24.2 (22/91) | 20.3 (148/730) | 0.4104 | 0.7976 | 0.4776 to 1.332 |
FHb | 12.1 (11/91) | 8.9 (65/730) | 0.3363 | 0.7109 | 0.3602 to 1.403 |
PoD fluidb | 68.1 (62/91) | 76.3 (557/730) | 0.094 | 1.506 | 0.9385 to 2.417 |