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Table 3 Stability

From: Development and validation of an HPLC method for the determination of vancomycin in human plasma and its comparison with an immunoassay (PETINIA)

Stability (n = 5)

Nominal concentration (mg/L)

50 (HQC)

0.5 (LQC)

Short term stability a

Mean (mg/L)

48.5

0.51

SD

1.18

0.02

Recovery (%)

96.9

102.6

CV (%)

2.43

3.32

Freeze–thaw stability b

Mean (mg/L)

50.6

0.48

SD

4.73

0.06

Recovery (%)

108.2

96.8

CV (%)

8.74

11.4

Long term stability c

Mean (mg/L)

45.8

0.44

SD

0.8

0.02

Recovery (%)

91.7

87.5

CV (%)

1.75

4.94

  1. aAfter storage at room temperature for 24 h
  2. bAfter four freeze and thaw cycles
  3. cAfter storage at −20 °C for 3 months