Fig. 4From: Experimental vitamin B12 deficiency in a human subject: a longitudinal investigation of the performance of the holotranscobalamin (HoloTC, Active-B12) immunoassaySerum total vitamin B12 and MMA. a Serum total vitamin B12 and MMA versus time. b Serum total vitamin B12 versus MMA. Reference A B12 Low = low limit for serum vitamin B12 concentration defined by Oh and Brown (2003). Reference B B12 Low = low limit for serum vitamin B12 concentration defined by Bates and Lewis (2012). Lab B12 RI low = lower limit of serum vitamin B12 concentration reference interval defined by the testing laboratory. Lab MMA RI high = upper limit of plasma methylmalonic acid concentration reference interval defined by the testing laboratoryBack to article page