Table 2 Descriptive characteristics of women with stages I–III breast cancer by Asian/Pacific Islander ethnicity in the SEER 18 registries, 1991–2011
Non-Hispanic White women (n = 462,005) | Chinese (n = 8416) | Japanese (n = 7858) | Filipino (n = 11,193) | Hawaiian (n = 2569) | |
|---|---|---|---|---|---|
Age at index breast cancer | |||||
Mean (SD) | 61.2 (13.7) | 55.9 (13.5) | 61.7 (13.6) | 56.0 (12.1) | 57.0 (12.5) |
Median (IQR) | 61 (51–72) | 54 (46–66) | 62 (51–72) | 55 (47–64) | 57 (48–66) |
20–49 years | 102,558 (22.2) | 3164 (37.6) | 1719 (21.9) | 3628 (32.4) | 761 (29.6) |
50–64 years | 168,817 (36.5) | 2972 (35.3) | 2635 (33.5) | 4793 (42.8) | 1088 (42.4) |
65–74 years | 100,839 (21.8) | 1361 (16.2) | 1937 (24.7) | 1903 (17.0) | 490 (19.1) |
75–85 years | 70,659 (15.3) | 746 (8.9) | 1299 (16.5) | 753 (6.7) | 201 (7.8) |
85+ years | 19,132 (4.1) | 173 (2.1) | 268 (3.4) | 116 (1.0) | 29 (1.1) |
Birthplace | |||||
U.S. | 194,905 (42.2) | 930 (11.1) | 3838 (48.8) | 670 (6.0) | 2078 (80.9) |
Non-U.S. | 20,923 (4.5) | 4398 (52.3) | 1423 (18.1) | 7339 (65.6) | 22 (0.9) |
Unknown | 246,177 | 3088 | 2597 | 3184 | 469 |
Marital status | |||||
Single or never married | 47,135 (10.2) | 994 (11.8) | 972 (12.4) | 1429 (12.8) | 386 (15.0) |
Married or domestic partner | 400,184 (86.6) | 7252 (86.2) | 6772 (86.2) | 9523 (85.1) | 2131 (83.0) |
Unknown | 14,686 | 170 | 114 | 241 | 52 |
AJCC stage | |||||
I | 242,188 (52.4) | 4250 (50.5) | 4624 (58.8) | 5022 (44.9) | 1221 (47.5) |
II | 160,716 (34.8) | 3128 (37.2) | 2484 (31.6) | 4442 (39.7) | 959 (37.3) |
III | 59,101 (12.8) | 1038 (12.3) | 750 (9.5) | 1729 (15.4) | 389 (15.1) |
Hormone receptor status | |||||
ER(+)/PR(+) | 282,720 (61.2) | 5059 (60.1) | 5083 (64.7) | 6572 (58.7) | 1775 (69.1) |
ER(+)/PR(−) | 50,909 (11.0) | 869 (10.3) | 842 (10.7) | 1226 (11.0) | 224 (8.7) |
ER(−)/PR(+) | 6931 (1.5) | 152 (1.8) | 178 (2.3) | 190 (1.7) | 65 (2.5) |
ER(−)/PR(−) | 71,453 (15.5) | 1445 (17.2) | 1062 (13.5) | 1977 (17.7) | 371 (14.4) |
Missing | 49,992 | 891 | 693 | 1228 | 134 |
Tumor size | |||||
<2 cm | 365,185 (79.0) | 6685 (79.4) | 6259 (79.7) | 8534 (76.2) | 1911 (74.4) |
≥2 cm | 94,405 (20.4) | 1695 (20.1) | 1571 (20.0) | 2613 (23.3) | 651 (25.3) |
Missing | 2415 | 36 | 28 | 46 | 7 |
Lymph node status | |||||
Negative | 315,405 (68.3) | 5698 (67.7) | 5890 (75.0) | 7299 (65.2) | 1701 (66.2) |
Positive | 146,516 (31.7) | 2717 (32.3) | 1967 (25.0) | 3893 (34.8) | 867 (33.7) |
Missing | 84 | 1 | 1 | 1 | 1 |
Surgery | |||||
Radical or total mastectomy | 199,975 (43.3) | 4301 (51.1) | 3425 (43.6) | 6299 (56.3) | 1115 (43.4) |
Breast-conserving surgery | 223,197 (48.3) | 3510 (41.7) | 3536 (45.0) | 4326 (38.6) | 1180 (45.9) |
Unspecified surgery | 38,833 | 605 | 897 | 568 | 274 |
Radiation | |||||
No | 213,565 (46.2) | 4185 (49.7) | 3497 (44.5) | 5797 (51.8) | 1049 (40.8) |
Yes | 235,859 (51.1) | 4015 (47.7) | 4218 (53.7) | 5092 (45.5) | 1476 (57.5) |
Unknown | 12,581 | 216 | 143 | 304 | 44 |
Person-years of follow-up | |||||
Mean (SD) | 6.8 (4.9) | 6.9 (5.1) | 8.2 (5.4) | 6.6 (4.9) | 7.3 (5.2) |
Median (IQR) | 4 (2–6) | 3 (2–6) | 4 (2–6) | 3 (2–5) | 4 (2–6) |
Outcome status | |||||
Alive | 352,200 (76.2) | 7138 (84.8) | 6339 (80.7) | 9401 (84.0) | 1935 (75.3) |
Died (all causes) | 109,805 (23.8) | 1278 (15.2) | 1519 (19.3) | 1792 (16.0) | 634 (24.7) |
Breast cancer-specific | 46,116 (42.0) | 712 (55.7) | 554 (36.5) | 1061 (59.2) | 288 (45.4) |
Cardiovascular | 25,527 (23.2) | 207 (16.2) | 381 (25.1) | 272 (15.2) | 140 (22.1) |
Korean (n = 2755) | Vietnamese (n = 2410) | Asian Indian and Pakistani (n = 2908) | Pacific Islandera (n = 928) | Other Asiana (n = 5494) | |
|---|---|---|---|---|---|
Age at index breast cancer | |||||
Mean (SD) | 53.3 (11.9) | 52.6 (12.2) | 53.4 (12.8) | 55.0 (12.0) | 54.0 (12.5) |
Median (IQR) | 52 (45–62) | 51 (44–60) | 53 (44–62) | 55 (46–63) | 52 (45–62) |
20–49 years | 1173 (42.6) | 1078 (44.7) | 1180 (40.6) | 318 (34.3) | 2220 (40.4) |
50–64 years | 1060 (38.5) | 910 (37.8) | 1127 (38.8) | 402 (43.3) | 2124 (38.7) |
65–74 years | 372 (13.5) | 286 (11.9) | 434 (14.9) | 150 (16.2) | 750 (13.7) |
75–85 years | 135 (4.9) | 115 (4.8) | 144 (5.0) | 51 (5.5) | 345 (6.3) |
85+ years | 15 (0.5) | 21 (0.9) | 23 (0.8) | 7 (0.8) | 55 (1.0) |
Birthplace | |||||
U.S. | 124 (4.5) | 24 (1.0) | 135 (4.6) | 82 (8.8) | 543 (9.9) |
Non-U.S. | 1792 (65.0) | 1637 (67.9) | 1525 (52.4) | 488 (52.6) | 1333 (24.3) |
Unknown | 839 | 749 | 1248 | 358 | 3618 |
Marital status | |||||
Single or never married | 275 (10.0) | 396 (16.4) | 143 (4.9) | 110 (11.9) | 667 (12.1) |
Married or domestic partner | 2411 (87.5) | 1947 (80.8) | 2699 (92.8) | 793 (85.5) | 4650 (84.6) |
Unknown | 69 | 67 | 66 | 25 | 177 |
AJCC stage | |||||
I | 1270 (46.1) | 1071 (44.4) | 1195 (41.1) | 341 (36.7) | 2670 (48.6) |
II | 1085 (39.4) | 968 (40.2) | 1192 (41.0) | 395 (42.6) | 2202 (40.1) |
III | 400 (14.5) | 371 (15.4) | 521 (17.9) | 192 (20.7) | 622 (11.3) |
Hormone receptor status | |||||
ER(+)/PR(+) | 1525 (55.4) | 1302 (54.0) | 1722 (59.2) | 606 (65.3) | 3330 (60.6) |
ER(+)/PR(−) | 263 (9.5) | 258 (10.7) | 269 (9.3) | 80 (8.6) | 592 (10.8) |
ER(−)/PR(+) | 55 (2.0) | 53 (2.2) | 41 (1.4) | 13 (1.4) | 76 (1.4) |
ER(−)/PR(−) | 620 (22.5) | 493 (20.5) | 614 (21.1) | 170 (18.3) | 916 (16.7) |
Missing | 292 | 304 | 262 | 59 | 580 |
Tumor size | |||||
<2 cm | 2209 (80.2) | 1922 (79.8) | 2348 (80.7) | 709 (76.4) | 4671 (85.0) |
≥2 cm | 537 (19.5) | 473 (19.6) | 542 (18.6) | 209 (22.5) | 806 (14.7) |
Missing | 9 | 15 | 18 | 10 | 17 |
Lymph node status | |||||
Negative | 1766 (64.1) | 1560 (64.7) | 1749 (60.1) | 538 (58.0) | 3696 (67.3) |
Positive | 989 (35.9) | 848 (35.2) | 1157 (39.8) | 390 (42.0) | 1797 (32.7) |
Missing | 2 | 2 | |||
Surgery | |||||
Radical or total mastectomy | 1376 (49.9) | 1391 (57.7) | 1425 (49.0) | 459 (49.5) | 2767 (50.4) |
Breast-conserving surgery | 1235 (44.8) | 940 (39.0) | 1386 (47.7) | 427 (46.0) | 2569 (46.8) |
Unspecified surgery | 144 | 79 | 97 | 42 | 158 |
Radiation | |||||
No | 1345 (48.8) | 1325 (55.0) | 1288 (44.3) | 442 (47.6) | 2897 (52.7) |
Yes | 1347 (48.9) | 1027 (42.6) | 1539 (52.9) | 452 (48.7) | 2397 (43.6) |
Unknown | 63 | 58 | 81 | 34 | 200 |
Person-years of follow-up | |||||
Mean (SD) | 6.2 (4.7) | 6.1 (4.6) | 5.3 (4.2) | 5.2 (4.3) | 12 (0.2) |
Median (IQR) | 3 (2–5) | 3 (2–5) | 3 (1–4) | 2 (1–4) | 6 (0.1) |
Outcome status | |||||
Alive | 2430 (88.2) | 2088 (86.6) | 2564 (88.2) | 751 (80.9) | 5012 (91.2) |
Died (all causes) | 325 (11.8) | 322 (13.4) | 344 (11.8) | 177 (19.1) | 482 (8.8) |
Breast cancer-specific | 219 (67.4) | 211 (65.5) | 216 (62.8) | 101 (57.1) | 299 (5.4) |
Cardiovascular | 33 (10.2) | 23 (7.1) | 40 (11.6) | 20 (11.3) | 57 (1.0) |