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Table 3 Number of heavy chain variable regions that use the same V and J genes and have the same CDR3 length as known autoantibody from IMGT/LIGM-DB

From: Short-term assessment of BCR repertoires of SLE patients after high dose glucocorticoid therapy with high-throughput sequencing

Autoantibody accession no. IGHVs IGHJs CDR3 length P1-0 P1-1 P1-3 P2-0 P2-1 P2-3
AF035024 IGHV3-30 IGHJ4 6 AA 87 0 0 75 156 36
AF035021 IGHV3-30 IGHJ4 10 AA 1060 375 303 802 896 1353
L12105 IGHV1-2 IGHJ4 10 AA 14 36 38 136 379 227
AF035023 IGHV3-48 IGHJ3 11 AA 65 42 50 58 127 40
L12087 IGHV1-3 IGHJ4 11 AA 416 238 115 371 312 217
AF035020 IGHV3-48 IGHJ3 12 AA 235 0 198 95 183 96
AF035042 IGHV3-53 IGHJ4 12 AA 995 150 102 426 482 664
L12100 IGHV1-2 IGHJ6 12 AA 81 0 0 131 43 159
X54435 IGHV3-74 IGHJ5 12 AA 18 147 0 22 44 89
AF035018 IGHJ2-5 IGHJ4 13 AA 712 354 95 1471 850 792
AF035025 IGHV1-69 IGHJ2 13 AA 0 0 0 39 56 61
AF035041 IGHV4-59 IGHJ4 13 AA 961 248 362 1176 1393 1406
D16837 IGHV1-69 IGHJ4 13 AA 658 206 165 504 815 695
L12061 IGHV1-2 IGHJ4 13 AA 122 80 85 695 631 674
L12102 IGHV1-3 IGHJ4 13 AA 588 360 188 411 440 327
AF035043 IGHV3-43 IGHJ3 14 AA 76 35 77 131 114 126
L12090 IGHV3-53 IGHJ6 14 AA 180 0 113 148 84 116
L12098 IGHV1-3 IGHJ4 14 AA 743 419 138 598 437 449
X73856 IGHV1-8 IGHJ6 14 AA 88 0 0 55 99 160
AF035030 IGHV3-30 IGHJ4 15 AA 2939 1426 828 2052 2534 2339
S73912 IGHV3-21 IGHJ4 15 AA 5 0 0 0 0 0
M85255 IGHV3-30 IGHJ6 16 AA 1878 949 896 1225 1178 1138
U07194 IGHV1-2 IGHJ5 16 AA 50 0 24 163 84 85
AF035022 IGHV1-46 IGHJ4 17 AA 305 123 0 103 284 230
AF035040 IGHV6-1 IGHJ3 17 AA 0 0 162 36 19 0
L12096 IGHV1-69 IGHJ3 17 AA 44 33 23 175 167 164
U07196 IGHV4-61 IGHJ3 17 AA 0 0 0 0 0 0
X73851 IGHV1-2 IGHJ3 17 AA 0 29 5 147 93 126
X73857 IGHV4-31 IGHJ4 17 AA 160 98 204 0 0 0
AF035019 IGHV1-2 IGHJ3 18 AA 0 0 0 60 102 85
AF035027 IGHV3-9 IGHJ1 18 AA 0 0 0 8 24 8
X15611 IGHV1-18 IGHJ4 18 AA 382 154 13 300 277 228
D16833 IGHV3-74 IGHJ2 21 AA 0 0 0 0 0 29
X54445 IGHV4-4 IGHJ4 21 AA 0 0 0 0 0 0
X56592 IGHV4-34 IGHJ4 21 AA 265 95 122 321 170 371
X73859 IGHV3-23 IGHJ6 21 AA 517 200 75 403 583 329
AF035026 IGHV3-15 IGHJ4 22 AA 81 58 5 31 20 10
D84252 IGHV3-33 IGHJ6 22 AA 147 121 0 0 0 0
U07195 IGHV4-34 IGHJ5 22 AA 49 10 0 157 173 100
Total no.     13,921 5986 4386 12,525 13,249 12,929
Percent (%)     2.82 2.35 2.90 2.66 2.52 2.77