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Table 2 A comparison of blood biochemistry data between the EPO-resistant and non-EPO-resistant HD patients

From: Circulating growth arrest-specific protein 6 levels are associated with erythropoietin resistance in hemodialysis patients

Item

Non-EPO resistance

EPO resistance

P value

N

98

36

 

Ferritin (ng/ml)

445.4 ± 330.8

472.9 ± 310.0

0.668

SI (μg/dl)

62.6 ± 22.3

57.8 ± 24.8

0.293

TSAT (%)

25.6 ± 11.2

24.5 ± 10.0

0.618

TIBC (μg/dl)

257.7 ± 58.0

241.4 ± 64.0

0.167

i-PTH (pg/ml)

417.7 ± 460.0

514.0 ± 609.0

0.331

Hematocrit (%)

33.5 ± 2.4

31.3 ± 2.7

<0.001

Albumin (g/dl)

4.0 ± 0.3

3.9 ± 0.4

0.173

Phosphate (mg/dl)

5.3 ± 1.5

5.6 ± 1.5

0.233

Calcium (mg/dl)

9.4 ± 0.8

9.2 ± 0.9

0.224

Gas6 (ng/ml)

13.7 ± 3.2

15.4 ± 3.3

0.006

IL-6 (pg/ml)

2.1 ± 1.5

3.1 ± 3.1

0.009

hs-CRP (mg/l)

4.5 ± 5.5

12.7 ± 25.2

0.002

Kt/V

1.79 ± 0.29

1.73 ± 0.32

0.272

RBC fragility test (% of NaCl)

0.413 ± 0.05

0.417 ± 0.04

0.700

  1. Data are mean ± SD
  2. EPO erythropoietin, SI serum iron, TSAT transferring saturation, TIBC total iron-binding capacity, i-PTH intact parathyroid hormone, Gas6 growth arrest-specific 6, IL-6 Interleukin 6, Hs-CRP high sensitivity C-reactive protein, RBC red blood cell