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Table 1 Clinical characteristics of study subjects

From: Circulating growth arrest-specific protein 6 levels are associated with erythropoietin resistance in hemodialysis patients

Item

Healthy control

Hemodialysis patient

P value

N

85

134

 

Ferritin (ng/ml)

165.4 ± 110.0

453.9 ± 325.5

<0.001

SI (μg/dl)

91.3 ± 36.6

61.2 ± 23.0

<0.001

TSAT (%)

29.5 ± 17.3

25.4 ± 10.9

0.031

TIBC (μg/dl)

335.4 ± 62.9

252.6 ± 59.1

<0.001

i-PTH (pg/ml)

26.4 ± 12.9

445.7 ± 502.8

<0.001

Hematocrit (%)

40.0 ± 3.9

32.9 ± 2.5

<0.001

Albumin (g/dl)

4.56 ± 0.27

3.97 ± 0.36

<0.001

Phosphate (mg/dl)

3.59 ± 0.42

5.39 ± 1.48

<0.001

Calcium (mg/dl)

9.18 ± 0.37

9.33 ± 0.87

0.136

Gas6 (ng/ml)

6.65 ± 1.75

14.16 ± 3.28

<0.001

IL-6 (pg/ml)

1.15 ± 1.89

2.35 ± 2.05

<0.001

hs-CRP (mg/l)

0.9 ± 0.9

6.7 ± 14.0

0.002

RBC fragility test (% of NaCl)

0.426 ± 0.034

0.414 ± 0.049

0.075

  1. Data are mean ± SD
  2. SI serum iron, TSAT transferring saturation, TIBC total iron-binding capacity, i-PTH intact parathyroid hormone, Gas6 growth arrest-specific protein 6, IL-6 Interleukin 6, Hs-CRP high sensitivity C-reactive protein, RBC red blood cell