Alcohol and breast cancer tumor subtypes in a Spanish Cohort

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Table 4 Associations between alcohol consumption and breast cancer by grade and tumor histology

Alcohol intake	Controls	GRADE			HISTOLOGY
	Controls	Grade I	Grade II	Grade III	Ductal	Lobular
	N	Cases OR^a (95 %CI)	Cases OR^a (95 % CI)	Cases OR^a (95 % CI)	Cases OR^a (95 % CI)	Cases OR^a (95 % CI)
Abstainers	389	112 1.0	290 1.0	159 1.0	535 1.0	57 1.0
Light/Moderate drinkers	293	109 1.22 (0.90, 1.67)	225 0.99 (0.78, 1.25)	130 1.06 (0.80,1.40)	436 1.05 (0.86, 1.29)	49 1.04 (0.69, 1.59)
Heavy drinkers^b	65	41 1.98 (1.26, 3.10)	120 2.34 (1.66, 3.31)	58 2.16 (1.44, 3.25)	205 2.21 (1.61, 3.03)	29 2.76 (1.62, 4.69)
		P = 0.007	P < 0.001	P = 0.003	P < 0.001	P = 0.003

^aPolytomous regression analysis. Adjusted for age at diagnosis, age at menarche, parity, breastfeeding, oral contraceptive use, menopausal status, BMI, smoking status, and family history
^bStudy subjects who consumed 1–7 drinks/week were considered light/moderate drinkers, and those who consumed >7drinks/week were considered heavy drinkers