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Table 4 Associations between alcohol consumption and breast cancer by grade and tumor histology

From: Alcohol and breast cancer tumor subtypes in a Spanish Cohort

Alcohol intake Controls GRADE HISTOLOGY
Grade I Grade II Grade III Ductal Lobular
N Cases ORa (95 %CI) Cases ORa (95 % CI) Cases ORa (95 % CI) Cases ORa (95 % CI) Cases ORa (95 % CI)
Abstainers 389 112 1.0 290 1.0 159 1.0 535 1.0 57 1.0
Light/Moderate drinkers 293 109 1.22 (0.90, 1.67) 225 0.99 (0.78, 1.25) 130 1.06 (0.80,1.40) 436 1.05 (0.86, 1.29) 49 1.04 (0.69, 1.59)
Heavy drinkersb 65 41 1.98 (1.26, 3.10) 120 2.34 (1.66, 3.31) 58 2.16 (1.44, 3.25) 205 2.21 (1.61, 3.03) 29 2.76 (1.62, 4.69)
  P = 0.007 P < 0.001 P = 0.003 P < 0.001 P = 0.003
  1. aPolytomous regression analysis. Adjusted for age at diagnosis, age at menarche, parity, breastfeeding, oral contraceptive use, menopausal status, BMI, smoking status, and family history
  2. bStudy subjects who consumed 1–7 drinks/week were considered light/moderate drinkers, and those who consumed >7drinks/week were considered heavy drinkers