Table 1 Characteristics of breast cancer patients and controls included in the study
From: Alcohol and breast cancer tumor subtypes in a Spanish Cohort
Cases N = 1766 (%) | Controls N = 833 (%) | |
|---|---|---|
Age, year | 56.3 ± 12.3 | 53.2 ± 13.2 |
Age at menarche, year | 13.2 ± 1.8 | 13.0 ± 1.7 |
Menopausal status | ||
Postmenopausal | 1088 (65.0) | 473 (58.0) |
Premenopausal | 587 (35.0) | 342 (42.0) |
Family historya | ||
No | 1459 (84.9) | 735 (91.4) |
Yes | 259 (15.1) | 69 (8.6) |
Age at firts full-term pregnancy, year | 24.8 ± 4.9 | 24.6 ± 5.2 |
Parity | ||
No | 307 (17.5) | 86 (10.5) |
Yes | 1443 (82.5) | 730 (89.5) |
Number of pregnancies | 2.0 ± 1.4 | 1.9 ± 1.2 |
Breastfeeding | ||
No | 782 (46.5) | 340 (41.7) |
Yes | 900 (53.5) | 475 (58.3) |
Lifetime breastfeeding, months | 6.0 ± 10.8 | 6.6 ± 11.0 |
Body mass index, kg/m2 | 25.7 ± 4.5 | 26.6 ± 4.8 |
Oral contraceptive use | ||
Never | 994 (60.5) | 424 (52.1) |
Ever | 649 (39.5) | 390 (47.9) |
Alcohol frequency | ||
0 drinks/week | 752 [46.1] | 417 [50.4] |
1–7 drinks/week | 607 [37.3] | 319 [38.5] |
>7 drinks/week | 270 [16.6] | 92 [11.1] |
Smoking status | ||
No | 1124 [68.2] | 542 [65.2] |
Ex-smoker | 268 [16.3] | 147 [17.7] |
Current smoker | 256 [15.5] | 142 [17.1] |
Hormone replacement therapy | ||
Never | 1456 (90.3) | 719 (91.1) |
Ever | 156 (9.7) | 70 (8.9) |
Grade | ||
I | 353 (22.3) | |
II | 808 (51.1) | |
III | 421 (26.6) | |
Histology type | ||
Ductal invasive | 1493 (85.2) | |
Lobular invasive | 164 (9.4) | |
Other | 95 (5.4) | |
Tumor size (2.4 ± 1.6) cm | ||
ER | ||
Positive | 1321 (79.3) | |
Negative | 345 (20.7) | |
PR | ||
Positive | 1093 (66.2) | |
Negative | 559 (33.8) | |
ER/PR/HER2 | ||
ER+/or PR+/HER2− | 952 (67.3) | |
ER+/or PR+/HER2+ | 178 (12.6) | |
ER−/PR−/HER2− | 204 (14.4) | |
ER−/PR−/HER2+ | 80 (5.7) | |