Skip to main content

Table 1 Clinicopathological features of 46 patients with SCC of EAC and their correlation to tumor growth pattern and budding grade

From: Tumor budding and laminin5-γ2 in squamous cell carcinoma of the external auditory canal are associated with shorter survival

  All Tumor budding Budding grade
n (%) Absent
13 (28.3)
Present
33 (71.7)
P value Low
39 (84.8)
High
7 (15.2)
P value
Mean age [years, (sd)] 62.5 (±11.4) 65.0 (±3.1) 61.5 (±1.9) 0.358 63.1 (±1.8) 59.3 (±0.4.3) 0.426
M:F 21:25 (46:54) 8:5 (62:38) 17:16 (52:48) 0.743 21:18 (54:46) 4:3 (57:43) 1.000
T
 T1 1 (2.2)       
 T2 12 (26.1) 4 (30.8) 9 (27.3)   11 (28.2) 2 (28.6)  
 T3 9 (19.5)       
 T4 24 (52.2) 9 (69.2) 24 (72.7) 1.000 28 (84.8) 5 (71.4) 1.000
N
 N0 36 (78.3) 11 (84.6) 25 (75.8)   31 (79.5) 5 (71.4)  
 N+ 10 (21.7) 2 (15.4) 8 (24.2) 0.700 8 (20.5) 2 (28.6) 0.636
M
 M0 44 (95.7) 13 (100) 31 (94.0)   38 (97.4) 6 (85.7)  
 M+ 2 (4.3) 0 (0) 2 (6.0) 1.000 1 (2.6) 1 (14.3) 0.284
TNM stage
 Stage I 1 (2.2)       
 Stage II 10 (21.7) 4 (30.8) 7 (21.2)   10 (25.6) 1 (14.3)  
 Stage III 10 (21.7)       
Stage IV 25 (54.4) 9 (69.2) 26 (78.8) 0.702 29 (74.4) 6 (85.7) 1.000
Differentiation
 Well 28 (60.9) 7 (53.8) 21 (63.6)   26 (66.7) 2 (28.6)  
 Moderate 15 (32.6) 6 (46.2) 9 (27.3)   11 (28.2) 4 (57.1)  
 Poor 3 (6.5) 0 (0) 3 (9.1) 0.309 2 (5.1) 1 (14.3) 0.157
Recurrence 21       
 Free 15 (71.4) 4 (80.0) 11 (68.8)   15 (78.9) 0 (0)  
 Recurrence 6 (28.6) 1 (20.0) 5 (31.2) 1.000 4 (21.1) 2 (100) 0.071
Effect of therapy 18       
 Grade 0–2 11 (61.1) 1 (25.0) 10 (71.4)   9 (60.0) 2 (66.7)  
 Grade 3 7 (38.9) 3 (75.0) 4 (28.6) 0.245 6 (40.0) 1 (33.3) 1.000
  1. M male, F female, MCF middle cranial fossa