Skip to main content

Table 3 Study results

From: Prediction of extubation failure in newborns, infants and children: brief report of a prospective (blinded) cohort study at a tertiary care paediatric centre in India

Parameters

Group A (extubation success; n = 66)

Group B (extubation failure; n = 26)

Probability

(p value)

Cough reflex

 Good

33

1

0.001

 Poor

33

25

Consistency of secretion

 Thick

21

15

0.022

 Thin

45

11

Amount of secretion

 Plenty

7

6

0.122

 Minimal

59

20

Sedation

 Yes

45

13

0.104

 No

21

13

Ionotropes

 Yes

49

18

0.627

 No

17

8

Spontaneous breathing trial (SBT)

 Passed

48

9

0.001

 Fail

0

7

Spontaneous respiratory rate (per minute)

31 (8–90)a

37 (8–76)a

0.298

Base excess

−1.7 (−18.8–6.6)a

−3.3 (−10.3–1.6)a

0.017

Serum lactate

1.7 (0.6–6.6)a

1.7 (0.7 5.1)a

0.883

Expiratory time

2.6 (0.91–9.55)a

2.6 (0.95–11.5)a

0.872

Duration of ventilation (in hours)

66 (13–314.5)a

52.5 (13–247.5)a

0.422

Rapid shallow breathing index (RSBI)

91 (58–173)a

169 (67–564)a

0.001

Hemoglobin (gm/dL)

12.96 ± 2.82b

12.68 ± 3.13b

0.679

SpO2

96.68 ± 2.32b

96.54 ± 3.06b

0.809

pH

7.38 ± 0.07b

7.36 ± 0.06b

0.339

PaCO2

37.64 ± 6.84b

37.65 ± 6.82b

0.994

Bicarbonate (HCO3)

21.64 ± 3.96b

20.89 ± 3.16b

0.397

Inspiratory time

0.52 ± 0.16b

0.49 ± 0.12b

0.444

Positive inspiratory pressure (PIP)

14.71 ± 2.72b

15.08 ± 1.87b

0.533

Positive end expiratory pressure (PEEP)

5.68 ± 1.78b

5.78 ± 0.81b

0.729

Fraction of inspired oxygen (FiO2)

0.31 ± 0.09b

0.33 ± 0.12b

0.391

Mean airway pressure (MAP)

7.13 ± 1.32b

7.29 ± 1.14b

0.769

Ventilator index (VI)

6.94 ± 4.49b

6.94 ± 4.49b

0.996

Continuous positive airway pressure (CPAP)

6.11 ± 0.78b

6.11 ± 0.32b

1.0

  1. [Cough reflex (p = 0.001) and thick secretions (p = 0.022) has shown strong relationship extubation failure. We also found that all patients who passed SBT were successfully extubated, whereas all patients who failed SBT ultimately failed extubation (p = 0.001). Similarly higher RSBI was associated with extubation failure (p = 0.001)]
  2. N.B.: a median values (minimum–maximum)
  3. b mean value ± SD