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Table 3 Tibio-femoral mechanical angle malalignment (cTFmA)

From: Does malalignment affect revision rate in total knee replacements: a systematic review of the literature

Author

RAQ criteria for radiological bias

Association between malalignment and worse outcome

Sample size

Alignment data

Findings

Parratte et al. (2010)

Low risk

No

398

292 knees classed as mechanically aligned 0° ± 3. 10 knees in the outlier group (beyond 0° ÷ 3°

15.4 % revision rate in the mechanically aligned group. 13 % in the outlier group (p = 0.88). No association between malalignment and revision

Bonner et al. (2011)

Low risk

No

458

372 knees were classified as mechanically aligned (0° ± 3°). 86 knees were within the malaligned group

33 revisions for aseptic loosening. Kaplan–Meier survival analysis showed a weak tendency towards improved survival with restoration of a neutral mechanical axis, but this did not reach statistical significance (p = 0.47)

Magnussen et al. (2011)

Low risk

No

553

181 patients were in varus alignment, 352 were in neutral alignment and 20 were in valgus alignment

No statistically significant difference in revision rates between the three groups (p = 0.15)