Fig. 1

Different possible types of inter-postsynaptic functional LINKs for perception. a Innate genetically determined and stabilized hemifused postsynaptic membranes B and D (A and C are the presynaptic terminals); b two synapses A–B and C–D are shown close to each other with their postsynaptic terminals B and D separated from each other by a hydrophilic region; c rapidly reversible direct contact between the postsynaptic membranes B and D by excluding the inter-membrane hydrophilic medium; d rapidly reversible partial inter-postsynaptic membrane hemifusion. Note the partial hemifusion between the postsynaptic membranes B and D. Since changes associated with perception require to be reversed rapidly back to the ground state at physiological time-scales for continuous perception to occur at the same locations (for perceiving rapidly changing percepts from the environment), the ideal nature of inter-postsynaptic functional LINK is expected to be of the type (a) or (c). NT: Neurotransmitter (modified from Vadakkan 2015a)