Fig. 1
From: A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment
Comparative sections of the maculae in wildtype and Otog vbd/vbd adult mice (P90). On saccular maculae of the control mouse (a), the otoconial membrane (layer of otoconia + hair bundles) is visible. In contrast, in Otog vbd/vbd mice (b), only few remnants of the otoconial membrane (probably remnants of hair bundles) are present. The supporting cells (SC) at the base of the maculae are preserved. It seems that sensory cells (HC) are affected, as shown by the drastic decrease in the number of hair bundle. BM basement membrane. (Magnification: ×40)