Skip to main content

Advertisement

Table 2 Genes showing differential expression between nulliparous and parous tumors as determined by real time PCR

From: High incidence of triple negative breast cancers following pregnancy and an associated gene expression signature

  Nulliparous Recent pregnancy Distant pregnancy Parous p value
CXCL1 1 ± 0.2 4.6 ± 1.1 4.7 ± 1.5 4.4 ± 1.6 0.005
THBS1 1 ± 0.2 0.5 ± 0.0 0.5 ± 0.1 0.5 ± 0.0 0.01
ESR1 1 ± 0.2 0.3 ± 0.0 0.2 ± 0.0 0.3 ± 0.1 0.01
ELN 1 ± 0.2 0.4 ± 0.0 0.4 ± 0.0 0.4 ± 0.1 0.018
TGFB3 1 ± 0.1 0.5 ± 0.0 0.5 ± 0.0 0.6 ± 0.1 0.022
ADAM9 1 ± 0.1 0.6 ± 0.0 0.6 ± 0.0 0.6 ± 0.0 0.025
IL11 1 ± 0.1 0.5 ± 0.0 0.5 ± 0.0 0.5 ± 0.1 0.026
CDH1 1 ± 0.1 0.5 ± 0.0 0.6 ± 0.0 0.5 ± 0.0 0.037
  1. Gene expression averages were normalized to the nulliparous group. Mean ± SE are shown. Parous includes recent and distant pregnancies. p value is for t test comparing nulliparous to parous. N nulliparous tumors = 19, N recent pregnancy tumors = 17, N distant pregnancy tumors = 17, N parous (combined recent and distant pregnancy) = 34